Adjusting Degree of Modification and Composition of gelAGE-Based Hydrogels Improves Long-Term Survival and Function of Primary Human Fibroblasts and Endothelial Cells in 3D Cultures.

Humans Hydrogels / chemistry Endothelial Cells Fibroblasts Collagen / chemistry Gelatin / chemistry Polyethylene Glycols / chemistry

Journal

Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849

Informations de publication

Date de publication:
13 03 2023
Historique:
pubmed: 15 2 2023
medline: 15 3 2023
entrez: 14 2 2023
Statut: ppublish

Résumé

This study aimed to develop a suitable hydrogel-based 3D platform to support long-term culture of primary endothelial cells (ECs) and fibroblasts. Two hydrogel systems based on allyl-modified gelatin (gelAGE), G

Identifiants

DOI: 10.1021/acs.biomac.2c01536 PMID: 36786807
pubmed: 36786807
doi: 10.1021/acs.biomac.2c01536
doi:

Substances chimiques

Hydrogels 0
Collagen 9007-34-5
Gelatin 9000-70-8
Polyethylene Glycols 3WJQ0SDW1A

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1497-1510

Auteurs

Hatice Genç (H)

Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Endowed Professorship for Nanomedicine, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.

Alessandro Cianciosi (A)

Department of Functional Materials in Medicine and Dentistry at the Institute of Functional Materials and Biofabrication (IFB), University of Würzburg and KeyLab Polymers for Medicine of the Bavarian Polymer Institute (BPI), Würzburg 97070, Germany.

Raphael Lohse (R)

Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Endowed Professorship for Nanomedicine, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.

Philipp Stahlhut (P)

Department of Functional Materials in Medicine and Dentistry at the Institute of Functional Materials and Biofabrication (IFB), University of Würzburg and KeyLab Polymers for Medicine of the Bavarian Polymer Institute (BPI), Würzburg 97070, Germany.

Jürgen Groll (J)

Department of Functional Materials in Medicine and Dentistry at the Institute of Functional Materials and Biofabrication (IFB), University of Würzburg and KeyLab Polymers for Medicine of the Bavarian Polymer Institute (BPI), Würzburg 97070, Germany.
ORCID: 0000-0003-3167-8466

Christoph Alexiou (C)

Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Endowed Professorship for Nanomedicine, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.

Iwona Cicha (I)

Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Endowed Professorship for Nanomedicine, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
ORCID: 0000-0002-7399-5307

Tomasz Jüngst (T)

Department of Functional Materials in Medicine and Dentistry at the Institute of Functional Materials and Biofabrication (IFB), University of Würzburg and KeyLab Polymers for Medicine of the Bavarian Polymer Institute (BPI), Würzburg 97070, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Adjusting Degree of Modification and...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Adjusting Degree of Modification and...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules endothéliales › Adjusting Degree of Modification and...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Fibroblastes › Adjusting Degree of Modification and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Collagène › Adjusting Degree of Modification and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Gélatine › Adjusting Degree of Modification and...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Polyéthylène glycols › Adjusting Degree of Modification and...