Squamous Cell Carcinoma of the Conjunctiva in a Patient With Previous Squamous Cell Carcinoma of the Lower Lip.

conjunctiva conjunctival carcinoma conjunctival tumor ocular surface squamous neoplasia squamous cell carcinoma (scc)

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Jan 2023
Historique:
accepted: 11 01 2023
entrez: 15 2 2023
pubmed: 16 2 2023
medline: 16 2 2023
Statut: epublish

Résumé

Squamous cell carcinoma (SCC) of the conjunctiva is a rare malignancy that is part of the spectrum of ocular surface squamous neoplasia (OSSN). Numerous non-modifiable and modifiable risk factors, such as male sex, age, cigarette smoking, and immunosuppression, have been identified. Any lesion of the conjunctiva requires a differential diagnosis between benign and malignant diseases, and all suspicious lesions should be biopsied. We present a case of SCC of the conjunctiva in a former smoker with multiple risk factors, including a previous SCC of the lower lip. Metastatic tumors rarely occur in the conjunctiva, but due to our patient's medical history, the exclusion of metastasis from the previous primary tumor was performed through whole-body imaging restaging.  The patient underwent a no-touch wide resection, followed by adjuvant topical chemotherapy with 5-fluorouracil (5-FU). After finishing treatment, the patient continues to attend regular ophthalmology and oncology appointments. Increasing population awareness of modifiable risk factors for OSSN is essential. Misdiagnosis can lead to a loss of time in treatment and progression of the disease.

Identifiants

pubmed: 36788816
doi: 10.7759/cureus.33642
pmc: PMC9912856
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e33642

Informations de copyright

Copyright © 2023, Chow Liu et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Patricia Chow Liu (P)

Oncology, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, PRT.

Francisca Bragança (F)

Ophthalmology, Centro Hospitalar Universitário do Porto, Porto, PRT.

Miguel Gomes (M)

Ophthalmology, Centro Hospitalar Universitário do Porto, Porto, PRT.

Marta Sousa (M)

Oncology, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, PRT.

Katia Ladeira (K)

Oncology, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, PRT.

Classifications MeSH