Incidence of Atrial Fibrillation in Large Vessel Occlusion and Large Embolic Stroke of Undetermined Source.

atrial fibrillation embolic stroke esus large vessel occlusion stroke

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Jan 2023
Historique:
accepted: 12 01 2023
entrez: 16 2 2023
pubmed: 17 2 2023
medline: 17 2 2023
Statut: epublish

Résumé

Large vessel occlusion (LVO) stroke is a common presentation of acute ischemic stroke and is often unknown or cryptogenic in etiology. There is a strong association between atrial fibrillation (AF) and cryptogenic LVO stroke, making it a unique stroke subgroup. Therefore, we propose that any LVO stroke meeting the criteria for an embolic stroke of an undetermined source (ESUS) be classified as large ESUS (LESUS). The purpose of this retrospective cohort study was to report the etiology of anterior LVO strokes that underwent endovascular thrombectomy. This was a single-center retrospective cohort study characterizing the etiology of acute anterior circulation LVO strokes that received emergent endovascular thrombectomy from 2011 to 2018. Patients with LESUS designation at hospital discharge were changed to cardioembolic etiology if AF was discovered during the two-year follow-up period.  Results: Overall, 155 (45%) of 307 patients in the study were found to have AF. New onset AF was discovered in 12 (23%) of 53 LESUS patients after hospitalization. Furthermore, eight (35%) of 23 LESUS patients who received extended cardiac monitoring were found to have AF. Nearly half the patients with LVO stroke who received endovascular thrombectomy were found to have AF. With the use of extended cardiac monitoring devices after hospitalization, AF is frequently discovered in patients with LESUS and may change the secondary stroke prevention strategy.

Identifiants

pubmed: 36793841
doi: 10.7759/cureus.33700
pmc: PMC9925036
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e33700

Informations de copyright

Copyright © 2023, Seachrist et al.

Déclaration de conflit d'intérêts

The authors have declared financial relationships, which are detailed in the next section.

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Auteurs

Eric J Seachrist (EJ)

Neurology, West Virginia University School of Medicine, Morgantown, USA.

Ashley Petrone (A)

Medicine, West Virginia University School of Medicine, Morgantown, USA.

Connor Nevin (C)

Medicine, West Virginia University School of Medicine, Morgantown, USA.

Tamra Ranasinghe (T)

Neurology, Wake Forest School of Medicine, Winston-Salem, USA.

Sneha Jacob (S)

Neurology, Wheeling Hospital, Wheeling, USA.

Christopher Ferari (C)

Urology, Indiana University School of Medicine, Indianapolis, USA.

Amelia Adcock (A)

Neurology, West Virginia University School of Medicine, Morgantown, USA.

Classifications MeSH