Viscoelastic coagulation testing in Neonatal Intensive Care Units: advantages and pitfalls in clinical practice.

Infant, Newborn Humans Intensive Care Units, Neonatal Blood Coagulation Tests Hemostasis Blood Coagulation Thrombelastography Hemostatics / therapeutic use Blood Coagulation Disorders / therapy

Journal

Blood transfusion = Trasfusione del sangue
ISSN: 2385-2070
Titre abrégé: Blood Transfus
Pays: Italy
ID NLM: 101237479

Informations de publication

Date de publication:
13 11 2023
Historique:
received: 05 09 2022
accepted: 01 12 2022
medline: 6 11 2023
pubmed: 17 2 2023
entrez: 16 2 2023
Statut: ppublish

Résumé

The expression "developmental hemostasis" indicates the age-related physiological changes occurring during the maturational process of the hemostatic system. Despite the quantitative and qualitative alterations, the neonatal hemostatic system is competent and well-balanced. Conventional coagulation tests do not provide reliable information as they only explore the procoagulants during the neonatal period. In contrast, viscoelastic coagulation tests (VCTs), such as viscoelastic coagulation monitoring (VCM), thromboelastography (TEG or ClotPro), and rotational thromboelastometry (ROTEM), are point-of-care assays that provide a quick, dynamic and global view of the hemostatic process, allowing prompt and individualized therapeutic intervention when necessary. Their use in neonatal care is on the increase and they could help monitor patients at risk of hemostatic derangement. In addition, they are crucial for anticoagulation monitoring during extracorporeal membrane oxygenation. Moreover, implementing VCT-based monitoring could optimize blood product use.

Identifiants

DOI: 10.2450/2023.0203-22 PMID: 36795342 PMC: PMC10645350
pubmed: 36795342
pii: 2023.0203-22
doi: 10.2450/2023.0203-22
pmc: PMC10645350
doi:

Substances chimiques

Hemostatics 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

538-548

Références

Eur J Pediatr. 2021 Dec;180(12):3455-3470
pubmed: 34131816
Diagnostics (Basel). 2021 Nov 25;11(12):
pubmed: 34943438
J Extra Corpor Technol. 2018 Sep;50(3):149-154
pubmed: 30250340
Semin Perinatol. 2018 Mar;42(2):80-88
pubmed: 29305227
Blood Transfus. 2021 Mar;19(2):113-119
pubmed: 33085599
J Clin Med. 2020 Nov 23;9(11):
pubmed: 33238649
Arch Dis Child. 2021 Jan 22;:
pubmed: 33483376
Int J Lab Hematol. 2016 May;38 Suppl 1:66-77
pubmed: 27426861
BMC Pediatr. 2014 Nov 03;14:277
pubmed: 25367591
Br J Haematol. 2016 Dec;175(5):784-828
pubmed: 27861734
Hematology Am Soc Hematol Educ Program. 2012;2012:506-11
pubmed: 23233626
Blood Adv. 2021 Dec 14;5(23):5202-5214
pubmed: 34555851
Eur J Pediatr. 2018 Mar;177(3):355-362
pubmed: 29255948
Crit Care. 2020 Jan 20;24(1):19
pubmed: 31959232
Am J Clin Pathol. 2006 Sep;126(3):400-5
pubmed: 16880137
Minerva Anestesiol. 2017 Apr;83(4):369-374
pubmed: 27858409
Clin Chem Lab Med. 2017 Aug 28;55(10):1592-1597
pubmed: 28306521
Transfusion. 2020 May;60(5):1069-1077
pubmed: 32315090
Thromb Res. 2019 Jan;173:172-177
pubmed: 29779622
Res Pract Thromb Haemost. 2020 May 15;4(4):455-468
pubmed: 32548547
Arch Dis Child Fetal Neonatal Ed. 2015 May;100(3):F270-4
pubmed: 25414486
Am J Hematol. 2014 Feb;89(2):228-32
pubmed: 24123050
Am J Clin Pathol. 2008 Jul;130(1):99-102
pubmed: 18550478
Pediatr Res. 2014 May;75(5):663-9
pubmed: 24522100
Pediatr Surg Int. 1997 Apr;12(4):289-92
pubmed: 9099648
Crit Care. 2013 Mar 19;17(2):218
pubmed: 23510484
Transfusion. 2014 Mar;54(3):627-32:quiz 626
pubmed: 23834237
Matern Health Neonatol Perinatol. 2015 Jun 16;1:16
pubmed: 27057333
JAMA. 2020 Aug 11;324(6):560-570
pubmed: 32780138
Arch Dis Child Fetal Neonatal Ed. 2014 Jul;99(4):F303-8
pubmed: 24646616
J Thromb Haemost. 2013 Oct;11(10):1850-4
pubmed: 23927605
J Thromb Haemost. 2004 Nov;2(11):2071-2
pubmed: 15550057
J Matern Fetal Neonatal Med. 2012 Oct;25 Suppl 4:18-21
pubmed: 22958005
Thromb Haemost. 2010 Feb;103(2):344-50
pubmed: 20076842
J Pediatr. 2021 Aug;235:92-99.e4
pubmed: 33836184
Front Pediatr. 2019 Sep 13;7:366
pubmed: 31572699
Front Pediatr. 2022 May 10;10:910646
pubmed: 35620150
J Thromb Haemost. 2003 Feb;1(2):263-8
pubmed: 12871499
Blood Coagul Fibrinolysis. 2004 Jan;15(1):103-7
pubmed: 15166952
Thromb Res. 2020 Aug;192:103-108
pubmed: 32464452
Clin Lab Med. 2014 Sep;34(3):655-73
pubmed: 25168949
J Pediatr Hematol Oncol. 2008 Mar;30(3):210-3
pubmed: 18376283
Blood. 1988 Nov;72(5):1651-7
pubmed: 3179444
Clin Perinatol. 2015 Sep;42(3):639-50
pubmed: 26250923
Haematologica. 2008 Aug;93(8):1256-9
pubmed: 18403390
Front Pediatr. 2021 Mar 02;9:627715
pubmed: 33738269
Front Pediatr. 2022 Mar 08;10:840288
pubmed: 35345614
Early Hum Dev. 2018 Dec;127:48-52
pubmed: 30312859
Neonatology. 2020;117(3):316-323
pubmed: 32485708
ASAIO J. 2021 Feb 1;67(2):196-200
pubmed: 33512915
J Vet Emerg Crit Care (San Antonio). 2009 Feb;19(1):3-10
pubmed: 19691581
J Matern Fetal Neonatal Med. 2015;28(15):1779-83
pubmed: 25245227
Front Pediatr. 2022 Aug 26;10:988681
pubmed: 36090551
Diagnostics (Basel). 2022 Jan 20;12(2):
pubmed: 35204352
Blood Coagul Fibrinolysis. 2011 Mar;22(2):110-7
pubmed: 21192254
J Matern Fetal Neonatal Med. 2021 Jan;34(2):195-200
pubmed: 30995877
Vox Sang. 2021 Apr;116(4):366-378
pubmed: 33245826
J Thromb Thrombolysis. 2021 May;51(4):989-996
pubmed: 32918670
Thromb Res. 2020 Jan;185:96-101
pubmed: 31786478
J Matern Fetal Neonatal Med. 2022 Dec;35(25):6998-7004
pubmed: 34304670
Pediatr Blood Cancer. 2016 May;63(5):839-43
pubmed: 26749087
Early Hum Dev. 2017 Dec;115:60-63
pubmed: 28923772
Transfus Apher Sci. 2009 Apr;40(2):119-23
pubmed: 19249246
Children (Basel). 2020 Nov 26;7(12):
pubmed: 33256197
Transfusion. 2020 Oct;60 Suppl 6:S75-S85
pubmed: 33089938
Semin Thromb Hemost. 2020 Jun;46(4):428-434
pubmed: 32438424
Front Pediatr. 2022 Nov 04;10:1041919
pubmed: 36405831
Br J Anaesth. 2015 Jan;114(1):91-102
pubmed: 25303988
Pediatrics. 2010 Feb;125(2):e300-8
pubmed: 20100756
Pediatr Surg Int. 2020 Sep;36(9):1027-1033
pubmed: 32607833
Eur J Pediatr. 2022 May;181(5):2173-2182
pubmed: 35211816
Blood. 1987 Jul;70(1):165-72
pubmed: 3593964
ASAIO J. 2021 Mar 1;67(3):254-262
pubmed: 33627598
Blood Rev. 2010 Mar;24(2):63-8
pubmed: 20074839
Arch Dis Child Fetal Neonatal Ed. 2017 Jan;102(1):F79-F84
pubmed: 27178714
Semin Thromb Hemost. 2003 Aug;29(4):329-38
pubmed: 14517745
Int J Lab Hematol. 2019 Aug;41(4):530-535
pubmed: 31062936
Clin Perinatol. 2015 Sep;42(3):613-23
pubmed: 26250921
ASAIO J. 2017 Jul/Aug;63(4):456-463
pubmed: 28557863
Arch Dis Child Fetal Neonatal Ed. 2020 Jul;105(4):412-418
pubmed: 31704736
Children (Basel). 2021 Oct 01;8(10):
pubmed: 34682143
J Clin Med. 2021 Oct 28;10(21):
pubmed: 34768556

Auteurs

Francesca Manzoni (F)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.

Genny Raffaeli (G)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.

Valeria Cortesi (V)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.

Giacomo S Amelio (GS)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Ilaria Amodeo (I)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Silvia Gulden (S)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Gaia Cervellini (G)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.

Andrea Tomaselli (A)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.

Marta Colombo (M)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.

Andrea Artoni (A)

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Stefano Ghirardello (S)

Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Fabio Mosca (F)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.

Giacomo Cavallaro (G)

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Nouveau-né › Viscoelastic coagulation testing in Neonatal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Viscoelastic coagulation testing in Neonatal...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Établissements de santé › Unités hospitalières › Unités de soins intensifs › Unités de soins intensifs pédiatriques › Unités de soins intensifs néonatals › Viscoelastic coagulation testing in Neonatal...
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Tests hématologiques › Tests de coagulation sanguine › Viscoelastic coagulation testing in Neonatal...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hémostase › Viscoelastic coagulation testing in Neonatal...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hémostase › Coagulation sanguine › Viscoelastic coagulation testing in Neonatal...
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Tests hématologiques › Tests de coagulation sanguine › Thromboélastographie › Viscoelastic coagulation testing in Neonatal...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents hématologiques › Coagulants › Hémostatiques › Viscoelastic coagulation testing in Neonatal...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Troubles de l'hémostase et de la coagulation › Viscoelastic coagulation testing in Neonatal...