Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4


Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
07 Feb 2023
Historique:
entrez: 17 2 2023
pubmed: 18 2 2023
medline: 18 2 2023
Statut: epublish

Résumé

Type I interferon (IFN) upregulates proteins that inhibit HIV within infected cells. Prior studies have identified IFN-stimulated genes (ISGs) that impede lab-adapted HIV in cell lines, yet the ISG(s) that mediate IFN restriction in HIV target cells, primary CD4

Identifiants

pubmed: 36798236
doi: 10.1101/2023.02.07.527545
pmc: PMC9934674
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIDA NIH HHS
ID : DP1 DA039543
Pays : United States
Organisme : NIAID NIH HHS
ID : F31 AI165168
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD103571
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007270
Pays : United States

Commentaires et corrections

Type : UpdateIn

Références

Nature. 2011 Apr 28;472(7344):481-5
pubmed: 21478870
J Virol. 2006 Jan;80(2):835-44
pubmed: 16378985
J Interferon Res. 1991 Dec;11(6):313-8
pubmed: 1686880
PLoS Pathog. 2022 Oct 10;18(10):e1010898
pubmed: 36215312
Cell Rep. 2020 Mar 17;30(11):3766-3777.e6
pubmed: 32187548
Retrovirology. 2015 Jan 09;12:1
pubmed: 25571928
Nature. 2013 Oct 24;502(7472):559-62
pubmed: 24048477
Hepatology. 2014 Apr;59(4):1262-72
pubmed: 23929627
Biochem J. 2010 Apr 14;427(3):523-34
pubmed: 20196774
J Exp Med. 2018 Mar 5;215(3):985-997
pubmed: 29436394
Cell Host Microbe. 2010 Jul 22;8(1):55-67
pubmed: 20638642
J Virol. 2015 Dec 30;90(6):3056-64
pubmed: 26719253
J Virol. 2011 Mar;85(5):2126-37
pubmed: 21177806
Nature. 2011 Dec 21;481(7381):365-70
pubmed: 22190034
Retrovirology. 2013 Oct 24;10:111
pubmed: 24156545
Nat Rev Immunol. 2012 Oct;12(10):687-95
pubmed: 22976433
J Virol. 2016 Jul 27;90(16):7469-7480
pubmed: 27279606
Elife. 2018 Dec 06;7:
pubmed: 30520725
Nature. 2016 Jul 7;535(7610):159-63
pubmed: 27383987
Nat Microbiol. 2021 Sep;6(9):1211
pubmed: 34389816
Cell Host Microbe. 2019 Jun 12;25(6):858-872.e13
pubmed: 31175045
Mol Ther Methods Clin Dev. 2020 Oct 27;20:30-38
pubmed: 33335945
Cell. 2013 Dec 19;155(7):1479-91
pubmed: 24360272
Nat Commun. 2017 Feb 10;8:14391
pubmed: 28186168
Cell Host Microbe. 2014 Dec 10;16(6):736-47
pubmed: 25464829
Sci Adv. 2018 Aug 01;4(8):eaat0843
pubmed: 30083606
Cell Rep. 2015 Feb 3;10(4):586-99
pubmed: 25620704
Biol Chem. 2006 Dec;387(12):1535-44
pubmed: 17132098
Cell Rep. 2016 Oct 25;17(5):1438-1452
pubmed: 27783955
Nat Microbiol. 2019 Dec;4(12):2044-2051
pubmed: 31636416
PLoS One. 2014 Jan 20;9(1):e85360
pubmed: 24465545
Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7112-7117
pubmed: 28630320
Virology. 1991 Dec;185(2):661-72
pubmed: 1683726
Cell Host Microbe. 2016 Oct 12;20(4):429-442
pubmed: 27640936
Nat Methods. 2022 Jan;19(1):81-89
pubmed: 34949807
PLoS Pathog. 2014 Jan;10(1):e1003895
pubmed: 24465210
Elife. 2018 Feb 16;7:
pubmed: 29451494
Nat Microbiol. 2016 Jul;1(7):16068
pubmed: 27375898
Nat Rev Microbiol. 2015 Jul;13(7):403-13
pubmed: 25915633
J Infect Dis. 2010 Jun 1;201(11):1686-96
pubmed: 20420510
PLoS Pathog. 2008 Feb 29;4(2):e1000007
pubmed: 18389079
Elife. 2018 Mar 28;7:
pubmed: 29590010
Science. 2002 Jun 21;296(5576):2215-8
pubmed: 12077416
AIDS. 1989 Jan;3(1):27-31
pubmed: 2496708
J Virol. 2010 May;84(9):4725-36
pubmed: 20164219
Nat Methods. 2017 Aug 31;14(9):831-832
pubmed: 28858339
Nat Protoc. 2019 Mar;14(3):756-780
pubmed: 30710114
Retrovirology. 2012 Jun 26;9:55
pubmed: 22734835
J Interferon Cytokine Res. 2011 Jan;31(1):119-30
pubmed: 21190487
Cell Rep. 2018 Feb 27;22(9):2493-2503
pubmed: 29490283
Nat Med. 2015 Dec;21(12):1502-7
pubmed: 26523972
Nat Protoc. 2019 Jan;14(1):1-27
pubmed: 30559373
J Infect Dis. 2012 May 1;205(9):1443-7
pubmed: 22454462
AIDS Res Hum Retroviruses. 1991 Apr;7(4):375-80
pubmed: 1906289
Bioinformatics. 2010 Jan 1;26(1):139-40
pubmed: 19910308
Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):E4571-80
pubmed: 24154727
Nat Commun. 2022 Apr 1;13(1):1752
pubmed: 35365639
EMBO J. 2002 Aug 1;21(15):3980-8
pubmed: 12145199
PLoS Pathog. 2015 Nov 03;11(11):e1005254
pubmed: 26529416
Science. 1986 Jul 11;233(4760):215-9
pubmed: 3014648
Cold Spring Harb Perspect Med. 2011 Sep;1(1):a006841
pubmed: 22229120
J Virol. 2014 Jul;88(14):7738-52
pubmed: 24760893
J Virol. 1999 Jul;73(7):5255-64
pubmed: 10364271
J Virol. 2009 Apr;83(8):3719-33
pubmed: 19176632
J Interferon Res. 1986 Apr;6(2):143-52
pubmed: 2425014
Nature. 2004 Feb 26;427(6977):848-53
pubmed: 14985764
Front Microbiol. 2022 Apr 12;13:854974
pubmed: 35495642
Cell Host Microbe. 2016 Apr 13;19(4):504-14
pubmed: 26996307
Nature. 2013 Oct 24;502(7472):563-6
pubmed: 24121441
Nature. 2012 Nov 1;491(7422):125-8
pubmed: 23000900
Science. 2014 Jan 24;343(6169):428-32
pubmed: 24356113
J Infect Dis. 2013 Jan 15;207(2):213-22
pubmed: 23105144
J Hematol Oncol. 2013 Oct 08;6(1):72
pubmed: 24191913
Cold Spring Harb Perspect Med. 2012 May;2(5):a006940
pubmed: 22553496
Front Immunol. 2018 Dec 06;9:2876
pubmed: 30574147
Nat Methods. 2018 Nov;15(11):941-946
pubmed: 30297964
Cell Host Microbe. 2013 Oct 16;14(4):398-410
pubmed: 24055605
PLoS One. 2012;7(12):e50859
pubmed: 23227216
Nucleic Acids Res. 2019 Jul 2;47(W1):W171-W174
pubmed: 31106371
J Virol. 2010 Sep;84(18):9254-66
pubmed: 20610724
Elife. 2018 Aug 07;7:
pubmed: 30084827
Annu Rev Immunol. 2014;32:513-45
pubmed: 24555472
Retrovirology. 2014 Oct 25;11:90
pubmed: 25348155
NAR Genom Bioinform. 2020 Sep;2(3):lqaa078
pubmed: 33015620

Auteurs

Hannah L Itell (HL)

Molecular and Cellular Biology PhD Program, University of Washington, Seattle, WA, 98109, USA.
Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA.

Daryl Humes (D)

Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA.
Present address: Tr1X Inc, La Jolla, CA, 92037, USA.

Julie Overbaugh (J)

Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA.

Classifications MeSH