Ex vivo RSA and Pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017.


Journal

Research square
Titre abrégé: Res Sq
Pays: United States
ID NLM: 101768035

Informations de publication

Date de publication:
06 Feb 2023
Historique:
entrez: 17 2 2023
pubmed: 18 2 2023
medline: 18 2 2023
Statut: epublish

Résumé

Malaria control is highly dependent on the effectiveness of artemisinin-based combination therapies (ACTs), the current frontline malaria curative treatments. Unfortunately, the emergence and spread of parasites resistant to artemisinin (ART) derivatives in Southeast Asia and South America, and more recently in Rwanda and Uganda (East Africa), compromise their long-term use in Sub-Saharan Africa where most malaria deaths occur. Here, we evaluated All samples tested in the Altogether, investigations combining

Identifiants

pubmed: 36798264
doi: 10.21203/rs.3.rs-2538775/v1
pmc: PMC9934778
pii:
doi:

Types de publication

Preprint

Langues

eng

Commentaires et corrections

Type : UpdateIn

Références

Genome Med. 2017 Jan 24;9(1):5
pubmed: 28118860
Nat Med. 2020 Oct;26(10):1602-1608
pubmed: 32747827
Lancet Infect Dis. 2021 Apr;21(4):e82-e92
pubmed: 33125913
N Engl J Med. 2018 Nov 15;379(20):1962-1964
pubmed: 30428283
Antimicrob Agents Chemother. 2015 Aug;59(8):5061-4
pubmed: 26033725
Sci Rep. 2020 Jun 1;10(1):8907
pubmed: 32483161
N Engl J Med. 2009 Jul 30;361(5):455-67
pubmed: 19641202
Sci Rep. 2019 Jul 23;9(1):10675
pubmed: 31337835
Antimicrob Agents Chemother. 2015 Oct 26;60(1):624-7
pubmed: 26503652
Clin Infect Dis. 2022 Sep 30;75(7):1242-1244
pubmed: 35213688
Antimicrob Agents Chemother. 2015 Jan;59(1):326-30
pubmed: 25348538
Lancet Infect Dis. 2021 Aug;21(8):1120-1128
pubmed: 33864801
BMC Infect Dis. 2020 Jul 22;20(1):533
pubmed: 32698879
Antimicrob Agents Chemother. 2019 Oct 22;63(11):
pubmed: 31427297
J Infect Dis. 2022 Apr 19;225(8):1411-1414
pubmed: 34216470
J Infect Dis. 2021 Mar 29;223(6):985-994
pubmed: 33146722
Malar J. 2020 May 24;19(1):191
pubmed: 32448203
Nature. 2014 Jan 2;505(7481):50-5
pubmed: 24352242
Emerg Infect Dis. 2021 Jan;27(1):294-296
pubmed: 33350925
Lancet Infect Dis. 2018 Mar;18(3):337-345
pubmed: 29398391
Emerg Infect Dis. 2018 Apr;24(4):718-726
pubmed: 29553316
Malar J. 2021 Jun 22;20(1):275
pubmed: 34158055
Malar J. 2020 Mar 30;19(1):134
pubmed: 32228566
Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0132021
pubmed: 34606334
Antimicrob Agents Chemother. 2017 Feb 23;61(3):
pubmed: 28069653
PLoS One. 2021 Mar 26;16(3):e0249357
pubmed: 33770151
Lancet Infect Dis. 2013 Dec;13(12):1043-9
pubmed: 24035558
Malar J. 2016 Nov 26;15(1):572
pubmed: 27887614
Malar J. 2014 Dec 04;13:472
pubmed: 25471113
N Engl J Med. 2021 Sep 23;385(13):1163-1171
pubmed: 34551228

Auteurs

Mamadou Samb Yade (MS)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Baba Dièye (B)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Romain Coppée (R)

Université Paris Cité and Sorbone Paris Nord, Inserm, IAME.

Aminata Mbaye (A)

Centre for Research and Training in Infectiology of Guinea (CRTIG).

Mamadou Alpha Diallo (MA)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Khadim Diongue (K)

Cheikh Anta Diop University of Dakar.

Justine Bailly (J)

University of Paris Cité, IRD, MERIT.

Atikatou Mama (A)

Université de Paris, Institut Cochin, Inserm U1016.

Awa Fall (A)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Alphonse Birane Thiaw (AB)

Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences.

Ibrahima Mbaye Ndiaye (IM)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Tolla Ndiaye (T)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Amy Gaye (A)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Abdoulaye Tine (A)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Younouss Diédhiou (Y)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Amadou Mactar Mbaye (AM)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Cécile Doderer-Lang (C)

Université de Strasbourg, UR7292 Dynamics of Host-Pathogen Interactions.

Mamane Nassirou Garba (MN)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Amy Kristine Bei (AK)

Yale School of Public Health.

Didier Ménard (D)

Université de Strasbourg, UR7292 Dynamics of Host-Pathogen Interactions.

Daouda Ndiaye (D)

Centre International de Recherche et de Formation en Génomique Appliquée, et de Surveillance Sanitaire (CIGASS), Cheikh Anta Diop University of Dakar.

Classifications MeSH