Assessment of Cardiovascular Risk in Women: Progress so Far and Progress to Come.

added value cardiovascular disease female-specific factors risk prediction sex differences

Journal

International journal of women's health
ISSN: 1179-1411
Titre abrégé: Int J Womens Health
Pays: New Zealand
ID NLM: 101531698

Informations de publication

Date de publication:
2023
Historique:
received: 01 12 2022
accepted: 03 02 2023
entrez: 17 2 2023
pubmed: 18 2 2023
medline: 18 2 2023
Statut: epublish

Résumé

Cardiovascular disease is the leading cause of death in women worldwide. Nonetheless, there exist several uncertainties in the prediction, diagnosis, and treatment of cardiovascular disease in women. A cornerstone in the prediction of cardiovascular disease is the implementation of risk scores. A variety of pregnancy- and reproductive-factors have been associated with lower or higher risk of cardiovascular disease. Consequently, the question has been raised, whether these female-specific factors also provide added value to cardiovascular risk prediction. In this review, we provide an overview of the existing literature on sex differences in the association of established cardiovascular risk factors with cardiovascular disease and the relation between female-specific factors and cardiovascular risk. Furthermore, we systematically reviewed the literature for studies that assessed the added value of female-specific factors beyond already established cardiovascular risk factors. Adding female-specific factors to models containing established cardiovascular risk factors has led to little or no significant improvement in the prediction of cardiovascular events. However, analyses primarily relied on data from women aged ≥40 years. Future investigations are needed to quantify whether pregnancy-related factors improve cardiovascular risk prediction in young women in order to support adequate treatment of risk factors and enhance prevention of cardiovascular disease in women.

Identifiants

pubmed: 36798791
doi: 10.2147/IJWH.S364012
pii: 364012
pmc: PMC9926980
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

191-212

Informations de copyright

© 2023 Tschiderer et al.

Déclaration de conflit d'intérêts

The authors report no conflicts of interest in this work.

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Auteurs

Lena Tschiderer (L)

Institute of Health Economics, Medical University of Innsbruck, Innsbruck, Austria.
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.

Lisa Seekircher (L)

Institute of Health Economics, Medical University of Innsbruck, Innsbruck, Austria.

Peter Willeit (P)

Institute of Health Economics, Medical University of Innsbruck, Innsbruck, Austria.
Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Sanne A E Peters (SAE)

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
The George Institute for Global Health, School of Public Health, Imperial College London, London, UK.
The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.

Classifications MeSH