Practice Patterns Regarding Female Reproductive Organ-Sparing and Nerve-Sparing Radical Cystectomy Among Urologic Oncologists in the United States.


Journal

Clinical genitourinary cancer
ISSN: 1938-0682
Titre abrégé: Clin Genitourin Cancer
Pays: United States
ID NLM: 101260955

Informations de publication

Date de publication:
08 2023
Historique:
received: 08 11 2022
revised: 16 01 2023
accepted: 22 01 2023
medline: 25 7 2023
pubmed: 22 2 2023
entrez: 21 2 2023
Statut: ppublish

Résumé

Female reproductive organ-sparing (ROS) and nerve-sparing radical cystectomy (RC) techniques have been shown to be oncologically safe and to improve sexual function outcomes among select patients with organ-confined disease. We sought to characterize practice patterns regarding female ROS and nerve-sparing RC among US urologists. We conducted a cross-sectional survey of members of the Society of Urologic Oncology to assess provider-reported frequency of ROS and nerve-sparing RC in premenopausal and postmenopausal patients with non-muscle-invasive bladder cancer that failed intravesical therapy or clinically localized muscle-invasive bladder cancer. Among 101 urologists, 80 (79.2%) reported that they routinely resect the uterus/cervix, 68 (67.3%) the neurovascular bundle, 49 (48.5%) the ovaries, and 19 (18.8%) a portion of the vagina when performing RC in premenopausal patients with organ-confined disease. When asked about changes to approach in postmenopausal patients, 71 participants (70.3%) reported that they were less likely to spare the uterus/cervix, 44 (43.6%) were less likely to spare the neurovascular bundle, 70 (69.3%) were less likely to spare the ovaries, and 23 (22.8%) were less likely to spare a portion of the vagina. We identified significant gaps in adoption of female ROS and nerve-sparing RC techniques for patients with organ-confined disease, despite evidence that ROS and nerve-sparing techniques are oncologically safe and can optimize functional outcomes in select patients. Future efforts should improve provider training in and education about ROS and nerve-sparing RC to improve postoperative outcomes among female patients.

Sections du résumé

BACKGROUND
Female reproductive organ-sparing (ROS) and nerve-sparing radical cystectomy (RC) techniques have been shown to be oncologically safe and to improve sexual function outcomes among select patients with organ-confined disease. We sought to characterize practice patterns regarding female ROS and nerve-sparing RC among US urologists.
PATIENTS AND METHODS
We conducted a cross-sectional survey of members of the Society of Urologic Oncology to assess provider-reported frequency of ROS and nerve-sparing RC in premenopausal and postmenopausal patients with non-muscle-invasive bladder cancer that failed intravesical therapy or clinically localized muscle-invasive bladder cancer.
RESULTS
Among 101 urologists, 80 (79.2%) reported that they routinely resect the uterus/cervix, 68 (67.3%) the neurovascular bundle, 49 (48.5%) the ovaries, and 19 (18.8%) a portion of the vagina when performing RC in premenopausal patients with organ-confined disease. When asked about changes to approach in postmenopausal patients, 71 participants (70.3%) reported that they were less likely to spare the uterus/cervix, 44 (43.6%) were less likely to spare the neurovascular bundle, 70 (69.3%) were less likely to spare the ovaries, and 23 (22.8%) were less likely to spare a portion of the vagina.
CONCLUSION
We identified significant gaps in adoption of female ROS and nerve-sparing RC techniques for patients with organ-confined disease, despite evidence that ROS and nerve-sparing techniques are oncologically safe and can optimize functional outcomes in select patients. Future efforts should improve provider training in and education about ROS and nerve-sparing RC to improve postoperative outcomes among female patients.

Identifiants

pubmed: 36801170
pii: S1558-7673(23)00032-0
doi: 10.1016/j.clgc.2023.01.010
pii:
doi:

Substances chimiques

Reactive Oxygen Species 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e236-e241

Subventions

Organisme : AHRQ HHS
ID : T32 HS026120
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001445
Pays : United States

Informations de copyright

Published by Elsevier Inc.

Auteurs

Natasha Gupta (N)

Department of Urology and Population Health, New York University and Manhattan Veterans Affairs, New York City, NY. Electronic address: natasha.gupta@nyulangone.org.

Lauren Kucirka (L)

Division of Maternal Fetal Medicine, Department of Gynecology and Obstetrics, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Alice Semerjian (A)

Trinity Health IHA, Ann Arbor, MI.

Phillip M Pierorazio (PM)

Department of Urology, University of Pennsylvania, Philadelphia, PA.

Stacy Loeb (S)

Department of Urology and Population Health, New York University and Manhattan Veterans Affairs, New York City, NY.

Trinity J Bivalacqua (TJ)

Department of Urology, University of Pennsylvania, Philadelphia, PA.

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