Crosstalk between Mfn2-mediated mitochondria associated membranes disorder and autophagy induced by molybdenum and cadmium in sheep heart.

Animals Sheep / genetics Molybdenum / metabolism Cadmium / metabolism Autophagy RNA, Messenger / genetics Mitochondria / metabolism
Autophagy Cadmium Mitochondria associated membranes Molybdenum

Journal

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
ISSN: 1873-6351
Titre abrégé: Food Chem Toxicol
Pays: England
ID NLM: 8207483

Informations de publication

Date de publication:
Apr 2023
Historique:
received: 11 12 2022
revised: 02 02 2023
accepted: 09 02 2023
pubmed: 22 2 2023
medline: 15 3 2023
entrez: 21 2 2023
Statut: ppublish

Résumé

To investigate the crosstalk of mitochondria associated membranes (MAMs) disorder and autophagy co-induced by molybdenum (Mo) and cadmium (Cd) in sheep hearts. A total of 48 sheep were randomly divided into 4 groups: control group, Mo group, Cd group and Mo + Cd group. The intragastric administration lasted for 50 days. The results showed that Mo or/and Cd exposure could cause morphological damage, imbalance of trace elements and antioxidant function, Ca

Identifiants

DOI: 10.1016/j.fct.2023.113660 PMID: 36803920
pubmed: 36803920
pii: S0278-6915(23)00062-5
doi: 10.1016/j.fct.2023.113660
pii:
doi:

Substances chimiques

Molybdenum 81AH48963U
Cadmium 00BH33GNGH
RNA, Messenger 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

113660

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Chengcheng Peng (C)

Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Economic and Technological Development District, Nanchang, 330045, Jiangxi, PR China; Department of Pharmacy, School of Medicine, Guangxi University of Science and Technology, 257 Liu-shi Road, Liuzhou, 545005, Guangxi, PR China.

Shuqiu Yang (S)

Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Economic and Technological Development District, Nanchang, 330045, Jiangxi, PR China.

Fan Yang (F)

Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Economic and Technological Development District, Nanchang, 330045, Jiangxi, PR China.

Zhiwei Xiong (Z)

Jiangxi Biotech Vocational College, Nanchang, 330045, Jiangxi, PR China.

Qiang Liu (Q)

Zhangshu Agriculture and Rural Affars Bureau, Zhangshu, PR China.

Shuxian Liao (S)

Fengxin County Modern Agricultural Technology Service Center, Fengxin, PR China.

Kai Huang (K)

Jiangxi Agricultural Engineering College, Zhangshu, PR China.

Wengen Wan (W)

Jiangxi Agricultural Technology Extension Center, Nanchang, PR China.

Huabin Cao (H)

Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Economic and Technological Development District, Nanchang, 330045, Jiangxi, PR China. Electronic address: chbin20020804@jxau.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Crosstalk between Mfn2-mediated mitochondria...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Ruminants › Ovis › Crosstalk between Mfn2-mediated mitochondria...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Molybdène › Crosstalk between Mfn2-mediated mitochondria...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Cadmium › Crosstalk between Mfn2-mediated mitochondria...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Autophagie › Crosstalk between Mfn2-mediated mitochondria...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN messager › Crosstalk between Mfn2-mediated mitochondria...
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Mitochondries › Crosstalk between Mfn2-mediated mitochondria...