Antioxidant activity in off and on-pump coronary artery bypass grafting and valve replacement surgery.
antioxidant
coronary artery disease
oxidative stress
superoxide dismutase
valvular heart disease
Journal
Journal of basic and clinical physiology and pharmacology
ISSN: 2191-0286
Titre abrégé: J Basic Clin Physiol Pharmacol
Pays: Germany
ID NLM: 9101750
Informations de publication
Date de publication:
01 May 2023
01 May 2023
Historique:
received:
07
09
2022
accepted:
23
01
2023
medline:
17
5
2023
pubmed:
23
2
2023
entrez:
22
2
2023
Statut:
epublish
Résumé
Cardiac surgeries initiate oxidative stress, increasing organ dysfunction development and mortality. The present study investigated the superoxide dismutase (SOD) activity, as an antioxidant enzyme, in patients undergoing coronary artery bypass (CABG) and heart valve replacement surgeries. A prospective study was performed on patients with proven coronary artery disease (CAD) or valvular heart disease (VHD) candidates for on- or off-pump CABG and valve replacement surgery. Serum SOD activity was measured preoperatively, at 24 h postoperatively, and at the time of discharge. In addition, echocardiography was performed before surgery and at discharge. A total of 48, 51, and 47 patients were enrolled in the on-pump, off-pump CABG, and valve replacement groups, respectively. Baseline serum SOD activity showed no significant association with BMI, age, and blood pressure in either CAD or VHD patients. The SOD values decreased at the 24 h postoperative time and then increased at the time of discharge in all groups, except for a slight decrease in the on-pump group. The changes in serum SOD values were not significantly different for the three surgical groups. The serum SOD activities fell significantly after CABG and valve replacement surgery. Further investigation is emphasized for the role of SOD in oxidative stress after cardiac surgery.
Identifiants
pubmed: 36804935
pii: jbcpp-2022-0244
doi: 10.1515/jbcpp-2022-0244
doi:
Substances chimiques
Antioxidants
0
Superoxide Dismutase
EC 1.15.1.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
365-370Informations de copyright
© 2023 Walter de Gruyter GmbH, Berlin/Boston.
Références
Gholoobi, A, Askari, VR, Naghedinia, H, Ahmadi, M, Vakili, V, Baradaran Rahimi, V. Colchicine effectively attenuates inflammatory biomarker high-sensitivity C-reactive protein (hs-CRP) in patients with non-ST-segment elevation myocardial infarction: a randomised, double-blind, placebo-controlled clinical trial. Inflammopharmacology 2021;29:1379–87, https://doi.org/10.1007/s10787-021-00865-0 .
doi: 10.1007/s10787-021-00865-0
Khameneh Bagheri, R, Najafi, MN, Ahmadi, M, Saberi, M, Maleki, M, Baradaran Rahimi, V. Investigation of the association between serum uric acid levels and HEART risk score in patients with acute coronary syndrome. Phys Rep 2022;10:e15513, https://doi.org/10.14814/phy2.15513 .
doi: 10.14814/phy2.15513
Gholoobi, A, Gifani, M, Akhlaghi, S, Pezeshki Rad, M, Baradaran Rahimi, V. Relationship between the prevalence and severity of non-alcoholic fatty liver disease and coronary artery disease: findings from a cross-sectional study of a referral center in northeast Iran. JGH Open 2022;6:330–7, https://doi.org/10.1002/jgh3.12746 .
doi: 10.1002/jgh3.12746
Bigdelu, L, Azari, A, Mashayekhi, Z, Dadgarmoghaddam, M, Baradaran Rahimi, V. A comparative study on the results of beating and arrested heart isolated tricuspid valve surgery: a cross-sectional study. Health Sci Rep 2022;5:e702, https://doi.org/10.1002/hsr2.702 .
doi: 10.1002/hsr2.702
Admans, LL, Jeynes, C, Clarke, J, Spyrou, NM. Elemental content of erythrocytes from patients undergoing Coronary Artery Bypass Grafting (CABG) surgery using PIXE analysis. J Radioanal Nucl Chem 2006;269:619–23, https://doi.org/10.1007/s10967-006-0274-7 .
doi: 10.1007/s10967-006-0274-7
Falsoleiman, H, Dehghani, M, Moohebati, M, Fazlinezhad, A, Daloee, MH, Alamdari, DH, et al.. Changes in pro-oxidant-antioxidant balance after bare metal and drug eluting stent implantation in patients with stable coronary disease. Clin Biochem 2011;44:160–4, https://doi.org/10.1016/j.clinbiochem.2010.10.009 .
doi: 10.1016/j.clinbiochem.2010.10.009
Baradaran Rahimi, V, Mousavi, SH, Haghighi, S, Soheili-Far, S, Askari, VR. Cytotoxicity and apoptogenic properties of the standardized extract of Portulaca oleracea on glioblastoma multiforme cancer cell line (U-87): a mechanistic study. Excli J 2019;18:165–86, https://doi.org/10.17179/excli2019-1063 .
doi: 10.17179/excli2019-1063
Ghadiri, M, Baradaran Rahimi, V, Moradi, E, Hasanpour, M, Clark, CCT, Iranshahi, M, et al.. Standardised pomegranate peel extract lavage prevents postoperative peritoneal adhesion by regulating TGF-β and VEGF levels. Inflammopharmacology 2021;29:855–68, https://doi.org/10.1007/s10787-021-00819-6 .
doi: 10.1007/s10787-021-00819-6
Kotur-Stevuljevic, J, Memon, L, Stefanovic, A, Spasic, S, Spasojevic-Kalimanovska, V, Bogavac-Stanojevic, N, et al.. Correlation of oxidative stress parameters and inflammatory markers in coronary artery disease patients. Clin Biochem 2007;40:181–7, https://doi.org/10.1016/j.clinbiochem.2006.09.007 .
doi: 10.1016/j.clinbiochem.2006.09.007
Rastan, AJ, Eckenstein, JI, Hentschel, B, Funkat, AK, Gummert, JF, Doll, N, et al.. Emergency coronary artery bypass graft surgery for acute coronary syndrome beating heart versus conventional cardioplegic cardiac arrest strategies. Circulation 2006;114(1 Suppl):I–477–85, https://doi.org/10.1161/circulationaha.105.001545 .
doi: 10.1161/circulationaha.105.001545
Afilalo, J, Rasti, M, Ohayon, SM, Shimony, A, Eisenberg, MJ. Off-pump vs. on-pump coronary artery bypass surgery: an updated meta-analysis and meta-regression of randomized trials. Eur Heart J 2012;33:1257–67, https://doi.org/10.1093/eurheartj/ehr307 .
doi: 10.1093/eurheartj/ehr307
Bigdelu, L, Poorzand, H, Azari, A, Jarahi, L, Ghaderi, F, Fazlinejad, A, et al.. Mitral leaflet separation to evaluate the severity of mitral stenosis: validation of the index by transesophageal three-dimensional echocardiography. Echocardiography 2018;35:361–7, https://doi.org/10.1111/echo.13805 .
doi: 10.1111/echo.13805
Rahsepar, AA, Pourghadamyari, H, Moohebati, M, Parizadeh, SMR, Tavallaie, S, Paydar, R, et al.. Prooxidant-anti-oxidant balance is not associated with extent of coronary artery disease. Clin Biochem 2011;44:1304–8, https://doi.org/10.1016/j.clinbiochem.2011.08.1133 .
doi: 10.1016/j.clinbiochem.2011.08.1133
Aydin, MS, Hazar, A, Kocarslan, A, Kucuk, A, Kaya, Z, Yuce, HH, et al.. Oxidative stress and inflammation are increased in first five days in coronary artery bypass surgery patients: a prospective study. Acta Med 2013;29:269.
Luyten, CR, Vanoverveld, F, Debacker, L, Sadowska, A, Rodrigus, I, Dehert, S, et al.. Antioxidant defence during cardiopulmonary bypass surgery. Eur J Cardio Thorac Surg 2005;27:611–6, https://doi.org/10.1016/j.ejcts.2004.12.013 .
doi: 10.1016/j.ejcts.2004.12.013
Jablonska, M, Sztanke, M, Pasternak, K, Dabrowski, W, Skowronska, M. Changes in antioxidant enzyme activities in erythrocytes in patients undergoing CABG - a pilot study. Appl Cardiopulm Pathophysiol 2008;12:13–9.
Chandrasena, LG, Peiris, H, Waikar, HD. Biochemical changes associated with reperfusion after off-pump and on-pump coronary artery bypass graft surgery. ACLS (Ann Clin Lab Sci) 2009;39:372–7.
Bolli, R. Causative role of oxyradicals in myocardial stunning: a proven hypothesis. Basic Res Cardiol 1998;93:156–62, https://doi.org/10.1007/s003950050079 .
doi: 10.1007/s003950050079
Moravvej, Z, Baradaran Rahimi, V, Azari, A, Rahsepar, AA, Ghayour-Mobarhan, M, Salehi, M, et al.. Changes in serum zinc and copper concentrations in patients with cardiovascular disease following cardiac surgery. Phys Rep 2022;10:e15483, https://doi.org/10.14814/phy2.15483 .
doi: 10.14814/phy2.15483
Haramaki, N, Stewart, DB, Aggarwal, S, Ikeda, H, Reznick, AZ, Packer, L. Networking antioxidants in the isolated rat heart are selectively depleted by ischemia-reperfusion. Free Radic Biol Med 1998;25:329–39, https://doi.org/10.1016/s0891-5849(98)00066-5 .
doi: 10.1016/s0891-5849(98)00066-5
Yaghoubi, A, Farzam, S, Pezeshkian, M, Nasiri, B, Azarfarin, R, Nouri, M, et al.. Comparison of oxidative stress content during on-pump and off-pump coronary artery bypass surgery. J Cardiovasc Thorac Res 2009;1:29–34.
Kurian, GA, Paddikkala, J. Effect of intra-operative magnesium supplementation in plasma antioxidant levels, trace elements and electrolyte balance in serum of coronary artery bypass graft patients. J Clin Basic Cardiol 2007;10:11–5.
Halliwell, B, Gutteridge, J, Cross, CE. Free radicals, antioxidants, and human disease: where are we now? J Lab Clin Med 1992;119:598–620.
Raja, SG, Dreyfus, GD. Current status of off-pump coronary artery bypass surgery. Asian Cardiovasc Thorac Ann 2008;16:164–78, https://doi.org/10.1177/021849230801600220 .
doi: 10.1177/021849230801600220
Wan, S, Izzat, MB, Lee, TW, Wan, IY, Tang, NL, Yim, AP. Avoiding cardiopulmonary bypass in multivessel CABG reduces cytokine response and myocardial injury. Ann Thorac Surg 1999;68:52–6, https://doi.org/10.1016/s0003-4975(99)00315-x .
doi: 10.1016/s0003-4975(99)00315-x
Gasz, B, Benko, L, Jancso, G, Lantos, J, Szanto, Z, Alotti, N, et al.. Comparison of inflammatory response following coronary revascularization with or without cardiopulmonary bypass. Exp Clin Cardiol 2004;9:26.
Al-Ruzzeh, S, Ambler, G, Asimakopoulos, G, Omar, RZ, Hasan, R, Fabri, B, et al.. Off-pump coronary artery bypass (OPCAB) surgery reduces risk-stratified morbidity and mortality: a United Kingdom multi-center comparative analysis of early clinical outcome. Circulation 2003;108:II–1–8, https://doi.org/10.1161/01.cir.0000087440.59920.a1 .
doi: 10.1161/01.cir.0000087440.59920.a1
Fransen, E, Maessen, J, Dentener, M, Senden, N, Geskes, G, Buurman, W. Systemic inflammation present in patients undergoing CABG without extracorporeal circulation. Chest 1998;113:1290–5, https://doi.org/10.1378/chest.113.5.1290 .
doi: 10.1378/chest.113.5.1290
Wan, S, Yim, APC. Cytokines in myocardial injury: impact on cardiac surgical approach. Eur J Cardio Thorac Surg 1999;16(1 Suppl):S107–11, https://doi.org/10.1016/s1010-7940(99)00200-6 .
doi: 10.1016/s1010-7940(99)00200-6
Biagioli, B, Borrelli, E, Maccherini, M, Bellomo, G, Lisi, G, Giomarelli, P, et al.. Reduction of oxidative stress does not affect recovery of myocardial function: warm continuous versus cold intermittent blood cardioplegia. Heart 1997;77:465–73, https://doi.org/10.1136/hrt.77.5.465 .
doi: 10.1136/hrt.77.5.465