Recommendations from a Canadian Delphi consensus study on best practice for optimal referral and appropriate management of severe asthma.

Asthma Biologics Canada Consensus development Consultation and referral Health care Primary care

Journal

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
ISSN: 1710-1484
Titre abrégé: Allergy Asthma Clin Immunol
Pays: England
ID NLM: 101244313

Informations de publication

Date de publication:
17 Feb 2023
Historique:
received: 29 12 2022
accepted: 02 02 2023
entrez: 22 2 2023
pubmed: 23 2 2023
medline: 23 2 2023
Statut: epublish

Résumé

In Canada, severe asthma affects an estimated 5-10% of people with asthma and is associated with frequent exacerbations, poor symptom control and significant morbidity from the disease itself, as well as the high dose inhaled, and systemic steroids used to treat it. Significant heterogeneity exists in service structure and patient access to severe asthma care, including access to biologic treatments. There appears to be over-reliance on short-acting beta agonists and frequent oral corticosteroid use, two indicators of uncontrolled asthma which can indicate undiagnosed or suboptimally treated severe asthma. The objective of this modified Delphi consensus project was to define standards of care for severe asthma in Canada, in areas where the evidence is lacking through patient and healthcare professional consensus, to complement forthcoming guidelines. The steering group of asthma experts identified 43 statements formed from eight key themes. An online 4-point Likert scale questionnaire was sent to healthcare professionals working in asthma across Canada to assess agreement (consensus) with these statements. Consensus was defined as high if ≥ 75% and very high if ≥ 90% of respondents agreed with a statement. A total of 150 responses were received from HCPs including certified respiratory educators, respirologists, allergists, general practitioners/family physicians, nurses, pharmacists, and respiratory therapists. Consensus amongst respondents was very high in 37 (86%) statements, high in 4 (9%) statements and was not achieved in 2 (5%) statements. Based on the consensus scores, ten key recommendations were proposed. These focus on referrals from primary and secondary care, accessing specialist asthma services, homecare provision for severe asthma patients and outcome measures. Implementation of these recommendations across the severe asthma care pathway in Canada has the potential to improve outcomes for patients through earlier detection of undiagnosed severe asthma, reduction in time to severe asthma diagnosis, and initiation of advanced phenotype specific therapies.

Sections du résumé

BACKGROUND BACKGROUND
In Canada, severe asthma affects an estimated 5-10% of people with asthma and is associated with frequent exacerbations, poor symptom control and significant morbidity from the disease itself, as well as the high dose inhaled, and systemic steroids used to treat it. Significant heterogeneity exists in service structure and patient access to severe asthma care, including access to biologic treatments. There appears to be over-reliance on short-acting beta agonists and frequent oral corticosteroid use, two indicators of uncontrolled asthma which can indicate undiagnosed or suboptimally treated severe asthma. The objective of this modified Delphi consensus project was to define standards of care for severe asthma in Canada, in areas where the evidence is lacking through patient and healthcare professional consensus, to complement forthcoming guidelines.
METHODS METHODS
The steering group of asthma experts identified 43 statements formed from eight key themes. An online 4-point Likert scale questionnaire was sent to healthcare professionals working in asthma across Canada to assess agreement (consensus) with these statements. Consensus was defined as high if ≥ 75% and very high if ≥ 90% of respondents agreed with a statement.
RESULTS RESULTS
A total of 150 responses were received from HCPs including certified respiratory educators, respirologists, allergists, general practitioners/family physicians, nurses, pharmacists, and respiratory therapists. Consensus amongst respondents was very high in 37 (86%) statements, high in 4 (9%) statements and was not achieved in 2 (5%) statements. Based on the consensus scores, ten key recommendations were proposed. These focus on referrals from primary and secondary care, accessing specialist asthma services, homecare provision for severe asthma patients and outcome measures.
CONCLUSIONS CONCLUSIONS
Implementation of these recommendations across the severe asthma care pathway in Canada has the potential to improve outcomes for patients through earlier detection of undiagnosed severe asthma, reduction in time to severe asthma diagnosis, and initiation of advanced phenotype specific therapies.

Identifiants

pubmed: 36804947
doi: 10.1186/s13223-023-00767-6
pii: 10.1186/s13223-023-00767-6
pmc: PMC9936462
doi:

Types de publication

Journal Article

Langues

eng

Pagination

12

Informations de copyright

© 2023. The Author(s).

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Auteurs

K Godbout (K)

Quebec Heart and Lung Institute, Laval University, Quebec City, Canada.

M Bhutani (M)

Department of Medicine, Division of Pulmonary Medicine, University of Alberta, Western Canada, Edmonton, AB, Canada.

L Connors (L)

Department of Medicine, Dalhousie University, Halifax, NS, Canada.

C K N Chan (CKN)

Faculty of Medicine, University of Toronto, Toronto, ON, Canada. charles.chan@onelinkconnect.com.

C Connors (C)

Canadian Network for Respiratory Care, Bolton, Canada.

D Dorscheid (D)

Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC, V6Z 1Y6, Canada.

G Dyck (G)

Clearspring Medical Clinic, Steinbach, MB, Canada.

V Foran (V)

Canadian Anesthesiologists' Society, Asthma Canada, Toronto, ON, M4S 2Z2, Canada.

A G Kaplan (AG)

Family Physician Airways Group of Canada, Respiratory Effectiveness Group, Department of Family and Community Medicine, University of Toronto, Toronto, L4G 1N2, Canada.

J Reynolds (J)

Interim CEO, Asthma Canada, Toronto, ON, M4S 2Z2, Canada.

S Waserman (S)

Department of Medicine, Clinical Immunology and Allergy, McMaster University, Hamilton, ON, Canada.

Classifications MeSH