The importance of the gut microbiota in the promotion, development, and treatment outcomes of cancer with special regard to the gut-respiratory axis.

The role of oral and pharyngeal microbiota is important in the promotion and development of head and neck cancers, as discussed in detail in this publication. The object of this work is to gather scientific information on the importance of the gut- respiratory axis in the promotion, development, and treatment outcome of head and neck cancer (HNSCC). Scientific knowledge about the interaction of head and neck cancer tumor cells and gut microbiota is residual, so examples of the relationship between the gut microbiota and the promotion of development in cases of other malignancies are also discussed. The subject of this work is also to present the importance of the gut-respiratory axis in promotion, development, and its impact on treatment outcomes of head and neck cancers.