"To Be or Not to Be Benign" at Partial Nephrectomy for Presumed RCC Renal Masses: Single-Center Experience with 195 Consecutive Patients.

benign renal mass laparoscopic partial nephrectomy tumor size

Journal

Diseases (Basel, Switzerland)
ISSN: 2079-9721
Titre abrégé: Diseases
Pays: Switzerland
ID NLM: 101636232

Informations de publication

Date de publication:
07 Feb 2023
Historique:
received: 15 11 2022
revised: 21 01 2023
accepted: 31 01 2023
entrez: 22 2 2023
pubmed: 23 2 2023
medline: 23 2 2023
Statut: epublish

Résumé

In daily medical practice, an increasing number of kidney masses are being incidentally detected using common imaging techniques, owing to the improved diagnostic accuracy and increasingly frequent use of these techniques. As a consequence, the rate of detection of smaller lesions is increasing considerably. According to certain studies, following surgical treatment, up to 27% of small enhancing renal masses are identified as benign tumors at the final pathological examination. This high rate of benign tumors challenges the appropriateness of surgery for all suspicious lesions, given the morbidity associated with such an intervention. The objective of the present study was, therefore, to determine the incidence of benign tumors at partial nephrectomy (PN) for a solitary renal mass. To meet this end, a total of 195 patients who each underwent one PN for a solitary renal lesion with the intent to cure RCC were included in the final retrospective analysis. A benign neoplasm was identified in 30 of these patients. The age of the patients ranged from 29.9-79 years (average: 60.9 years). The tumor size range was 1.5-7 cm (average: 3 cm). All the operations were successful using the laparoscopic approach. The pathological results were renal oncocytoma in 26 cases, angiomyolipomas in two cases, and cysts in the remaining two cases. In conclusion, we have shown in our present series the incidence rate of benign tumors in patients who have been subjected to laparoscopic PN due to a suspected solitary renal mass. Based on these results, we advise that the patient should be counseled not only about the intra- and post-operative risks of nephron-sparing surgery but also about its dual therapeutic and diagnostic role. Therefore, the patients should be informed of the considerably high probability of a benign histological result.

Identifiants

pubmed: 36810541
pii: diseases11010027
doi: 10.3390/diseases11010027
pmc: PMC9945135
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Raffaele Baio (R)

Department of Medicine and Surgery "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.

Giovanni Molisso (G)

Department of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.

Christian Caruana (C)

Department of Chemistry, University of Malta, MSD2080 Msida, Malta.

Umberto Di Mauro (U)

Department of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.

Olivier Intilla (O)

Department of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.

Umberto Pane (U)

Department of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.

Costantino D'Angelo (C)

Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.

Antonio Campitelli (A)

Department of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.

Francesca Pentimalli (F)

Department of Medicine and Surgery, LUM University, 70010 Bari, Italy.

Roberto Sanseverino (R)

Department of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.

Classifications MeSH