Plain language summary of the CheckMate 816 study results: nivolumab plus chemotherapy given before surgery for non-small-cell lung cancer.


Journal

Future oncology (London, England)
ISSN: 1744-8301
Titre abrégé: Future Oncol
Pays: England
ID NLM: 101256629

Informations de publication

Date de publication:
Mar 2023
Historique:
medline: 1 5 2023
pubmed: 24 2 2023
entrez: 23 2 2023
Statut: ppublish

Résumé

In this article, we summarize results from the ongoing phase 3 CheckMate 816 clinical study that were published in Adults who had not previously taken medications to treat NSCLC and whose cancer could be removed with surgery were included in CheckMate 816. During this study, a computer randomly assigned the treatment each person would receive before surgery for NSCLC. In total, 179 people were randomly assigned to receive Researchers found that people who Results from CheckMate 816 support the benefit of using

Identifiants

pubmed: 36815433
doi: 10.2217/fon-2023-0007
doi:

Substances chimiques

Nivolumab 31YO63LBSN
Ipilimumab 0

Banques de données

ClinicalTrials.gov
['NCT02998528']

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

549-557

Auteurs

Patrick M Forde (PM)

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins Kimmel Cancer Center, Baltimore, MD, USA.

Jonathan Spicer (J)

McGill University Health Center, Montréal, Québec, Canada.

Shun Lu (S)

Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Mariano Provencio (M)

Hospital Universitario Puerta de Hierro, Madrid, Spain.

Tetsuya Mitsudomi (T)

Kindai University Faculty of Medicine, Ohno-Higashi, Osaka-Sayama, Osaka, Japan.

Mark M Awad (MM)

Dana-Farber Cancer Institute, Boston, MA, USA.

Enriqueta Felip (E)

Vall d'Hebron Institute of Oncology, Barcelona, Spain.

Stephen R Broderick (SR)

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins Kimmel Cancer Center, Baltimore, MD, USA.

Julie R Brahmer (JR)

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins Kimmel Cancer Center, Baltimore, MD, USA.

Scott J Swanson (SJ)

Dana-Farber Cancer Institute, Boston, MA, USA.

Keith Kerr (K)

Aberdeen Royal Infirmary, Aberdeen, United Kingdom.

Changli Wang (C)

Tianjin Lung Cancer Center, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.

Tudor-Eliade Ciuleanu (TE)

Institutul Oncologic Prof. Dr. Ion Chiricuta & Universitatea de Medicina si Farmacie Iuliu Hatieganu, Cluj-Napoca, Romania.

Gene B Saylors (GB)

Charleston Oncology, Charleston, SC, USA.

Fumihiro Tanaka (F)

University of Occupational & Environmental Health, Kitakyushu, Japan.

Hiroyuki Ito (H)

Kanagawa Cancer Center, Yokohama, Japan.

Ke Neng Chen (KN)

Peking University School of Oncology, Beijing Cancer Hospital, Beijing, China.

Moishe Liberman (M)

Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada.

Everett E Vokes (EE)

University of Chicago Medicine, Chicago, IL, USA.

Janis M Taube (JM)

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins Kimmel Cancer Center, Baltimore, MD, USA.

Cecile Dorange (C)

Bristol Myers Squibb, Braine-L'Alleud, Belgium.

Junliang Cai (J)

Bristol Myers Squibb, Princeton, NJ, USA.

Joseph Fiore (J)

Bristol Myers Squibb, Princeton, NJ, USA.

Anthony Jarkowski (A)

Bristol Myers Squibb, Princeton, NJ, USA.

David Balli (D)

Bristol Myers Squibb, Princeton, NJ, USA.

Mark Sausen (M)

Bristol Myers Squibb, Princeton, NJ, USA.

Dimple Pandya (D)

Bristol Myers Squibb, Princeton, NJ, USA.

Christophe Y Calvet (CY)

Bristol Myers Squibb, Princeton, NJ, USA.

Nicolas Girard (N)

Institut du Thorax Curie-Montsouris, Institut Curie, Paris, France.

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Classifications MeSH