Higher stress response and altered quality of life in schizophrenia patients with low membrane levels of docosahexaenoic acid.
biomarkers
membrane fatty acids
quality of life
schizophrenia
stabilized patients
Journal
Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006
Informations de publication
Date de publication:
2023
2023
Historique:
received:
04
11
2022
accepted:
12
01
2023
entrez:
23
2
2023
pubmed:
24
2
2023
medline:
24
2
2023
Statut:
epublish
Résumé
Schizophrenia is a severe, chronic, and heterogeneous mental disorder that affects approximately 1% of the world population. Ongoing research aims at clustering schizophrenia heterogeneity into various "biotypes" to identify subgroups of individuals displaying homogeneous symptoms, etiopathogenesis, prognosis, and treatment response. The present study is in line with this approach and focuses on a biotype partly characterized by a specific membrane lipid composition. We have examined clinical and biological data of patients with stabilized schizophrenia, including the fatty acid content of their erythrocyte membranes, in particular the omega-3 docosahexaenoic acid (DHA). Two groups of patients of similar size were identified: the DHA- group (
Identifiants
pubmed: 36816405
doi: 10.3389/fpsyt.2023.1089724
pmc: PMC9937080
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1089724Informations de copyright
Copyright © 2023 Adrien, Bosc, Fumat, Tessier, Ferreri, Mouchabac, Tareste and Nuss.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Psychiatry Res. 2013 May 15;207(1-2):1-12
pubmed: 23068078
Am J Psychiatry. 2016 Jan;173(1):44-52
pubmed: 26472628
Schizophr Bull. 1994;20(3):433-40
pubmed: 7973464
Schizophr Res. 2012 Nov;141(2-3):153-61
pubmed: 22981812
Psychiatry Res. 1997 Oct 31;75(3):145-57
pubmed: 9437772
Schizophr Bull. 2013 Jul;39(4):830-8
pubmed: 22927668
Clin Neuropsychol. 1999 Aug;13(3):328-47
pubmed: 10726604
Schizophr Res. 1990 Jul-Aug;3(4):247-51
pubmed: 2278986
Sante Publique. 1997 Mar;9(1):35-44
pubmed: 9432414
Transl Psychiatry. 2016 Oct 4;6(10):e906
pubmed: 27701405
Nature. 2010 Nov 11;468(7321):187-93
pubmed: 21068826
Schizophr Bull. 2012 May;38(3):373-6
pubmed: 22461483
Schizophr Bull. 2016 Mar;42(2):358-68
pubmed: 26385764
Schizophr Bull. 2007 Nov;33(6):1277-83
pubmed: 17728265
Prim Care Companion CNS Disord. 2018 Sep 13;20(5):
pubmed: 30256544
Biol Psychiatry. 2008 Apr 15;63(8):801-8
pubmed: 18005941
Schizophr Res. 2014 Sep;158(1-3):230-5
pubmed: 24996507
Med Sci Sports Exerc. 1997 Jun;29(6 Suppl):S1-205
pubmed: 9243481
Lipids. 2015 Feb;50(2):121-9
pubmed: 25408476
Schizophr Res. 2011 Jun;129(1):57-65
pubmed: 21458237
Epidemiol Rev. 2008;30:67-76
pubmed: 18480098
PLoS One. 2013 Jul 24;8(7):e68717
pubmed: 23894336
Schizophr Res. 1994 Oct;13(3):195-207
pubmed: 7841132
Lipids Health Dis. 2013 May 28;12:79
pubmed: 23710642
Mol Psychiatry. 2004 Jul;9(7):684-97, 643
pubmed: 15098003
Diabetes Care. 1990 Apr;13(4):401-11
pubmed: 2318100
Can J Neurol Sci. 2016 Sep;43(5):665-71
pubmed: 27670209
Prostaglandins Leukot Essent Fatty Acids. 2012 Jul;87(1):35-41
pubmed: 22705264
Eur Psychiatry. 2017 Feb;40:65-75
pubmed: 27992836
Eur Psychiatry. 2018 Sep;53:37-45
pubmed: 29870894
J Hist Neurosci. 2002 Sep;11(3):265-77
pubmed: 12481477
Prog Neuropsychopharmacol Biol Psychiatry. 2001 Nov;25(8):1513-21
pubmed: 11642651
Obes Res. 1994 Nov;2(6):541-8
pubmed: 16355515
J Psychiatr Res. 2018 Sep;104:88-95
pubmed: 30005373
Am J Clin Nutr. 2022 Feb 9;115(2):422-431
pubmed: 34582547
Schizophr Res. 2000 Jun 16;43(2-3):109-16
pubmed: 10858629
Actas Esp Psiquiatr. 2015 Sep;43(5):170-6
pubmed: 26320895
Med Sci Sports Exerc. 2000 Jun;32(6):1119-24
pubmed: 10862539
J Clin Epidemiol. 1998 Nov;51(11):1013-23
pubmed: 9817119
Schizophrenia (Heidelb). 2022 Feb 25;8(1):7
pubmed: 35217671
Innov Clin Neurosci. 2017 Dec 1;14(11-12):77-81
pubmed: 29410941
Early Interv Psychiatry. 2021 Aug;15(4):874-881
pubmed: 32893462
Schizophr Bull. 2009 Mar;35(2):425-36
pubmed: 18990714
Acta Psychiatr Scand. 1998 Jan;97(1):36-41
pubmed: 9504701
J Clin Epidemiol. 1995 Aug;48(8):1051-60
pubmed: 7775992
Schizophr Res. 2000 Mar 16;42(1):7-17
pubmed: 10706981
Nature. 2014 Jul 24;511(7510):421-7
pubmed: 25056061
Neurology. 2012 Feb 28;78(9):658-64
pubmed: 22371413
Nord J Psychiatry. 2003;57(3):209-14
pubmed: 12775296
Schizophr Bull. 2009 Mar;35(2):381-2
pubmed: 19193741
Schizophr Bull. 1987;13(2):261-76
pubmed: 3616518
Br J Clin Psychol. 1999 Mar;38(1):27-41
pubmed: 10212735
Acta Psychiatr Scand. 1999 Sep;100(3):237-43
pubmed: 10493091
Psychiatry Res. 2011 Mar 30;186(1):23-7
pubmed: 20800904
Lancet Psychiatry. 2015 Mar;2(3):258-270
pubmed: 26359903
J Exp Psychol. 1948 Aug;38(4):404-11
pubmed: 18874598
Biol Psychiatry. 2004 Jul 1;56(1):41-5
pubmed: 15219471
Prostaglandins Leukot Essent Fatty Acids. 2022 Apr;179:102418
pubmed: 35366625
J Am Geriatr Soc. 2005 Apr;53(4):695-9
pubmed: 15817019
Schizophr Bull. 2018 Oct 17;44(6):1195-1203
pubmed: 29762765
Mol Psychiatry. 2019 Jun;24(6):776-794
pubmed: 29743584
Curr Top Behav Neurosci. 2020;44:49-66
pubmed: 31115797
Qual Life Res. 1992 Oct;1(5):349-51
pubmed: 1299467
Prog Lipid Res. 2008 Jan;47(1):15-36
pubmed: 17980916
Biol Psychiatry. 2002 Oct 15;52(8):823-30
pubmed: 12372654
Psychiatr Clin North Am. 2003 Mar;26(1):85-102
pubmed: 12683261
Schizophr Res. 2020 Dec;226:44-51
pubmed: 31301881
Curr Drug Discov Technol. 2013 Sep;10(3):245-53
pubmed: 21838664
Biochim Biophys Acta. 2012 May;1818(5):1309-17
pubmed: 22285120
Schizophr Res. 2003 Aug 1;62(3):195-204
pubmed: 12837515
Cell Metab. 2020 Apr 7;31(4):755-772.e7
pubmed: 32142670
J Clin Exp Neuropsychol. 2004 Apr;26(2):246-50
pubmed: 15202543
Int Clin Psychopharmacol. 1996 Jun;11 Suppl 3:89-95
pubmed: 8923116
Glob J Health Sci. 2014 Sep 18;6(7 Spec No):103-8
pubmed: 25363186
Encephale. 2001 Sep-Oct;27(5):444-9
pubmed: 11760694
Am J Psychiatry. 2016 Jan;173(1):3-4
pubmed: 26725337
J Lipid Res. 1965 Jul;6:428-31
pubmed: 14336214
Br J Psychiatry. 1995 May;166(5):654-9
pubmed: 7620753
Schizophr Res. 2004 Mar 1;67(1):23-31
pubmed: 14741321
Prev Med. 2010 Dec;51(6):488-93
pubmed: 20869985
J Clin Psychopharmacol. 2012 Apr;32(2):179-85
pubmed: 22367656
Br J Psychiatry. 2009 Feb;194(2):101-3
pubmed: 19182167
Antioxid Redox Signal. 2011 Oct 1;15(7):2011-35
pubmed: 21126177
Mol Psychiatry. 2000 May;5(3):332-6
pubmed: 10889539
Nat Commun. 2015 Aug 11;6:7934
pubmed: 26263244
Schizophr Bull. 2018 Aug 20;44(5):973-982
pubmed: 29648618
Lancet. 2009 Aug 22;374(9690):635-45
pubmed: 19700006
Schizophr Res. 2002 Nov 1;58(1):1-10
pubmed: 12363384
Brain. 2018 Jul 1;141(7):2213-2224
pubmed: 29860329
Prostaglandins Leukot Essent Fatty Acids. 2006 Sep;75(3):197-202
pubmed: 16828270
Prostaglandins Leukot Essent Fatty Acids. 2015 Jun;97:27-34
pubmed: 25921297
Dement Geriatr Cogn Dis Extra. 2013 Feb 16;3(1):25-36
pubmed: 23637698
Schweiz Z Sportmed. 1967;15(1):26-40
pubmed: 4383308