Dual-Bioorthogonal Catalysis by a Palladium Peptide Complex.

Humans Palladium Carcinoma, Non-Small-Cell Lung Lung Neoplasms Catalysis Metalloproteins

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
09 03 2023
Historique:
pubmed: 24 2 2023
medline: 11 3 2023
entrez: 23 2 2023
Statut: ppublish

Résumé

Artificial metalloenzymes (ArMs) enrich bioorthogonal chemistry with new-to-nature reactions while limiting metal deactivation and toxicity. This enables biomedical applications such as activating therapeutics

Identifiants

DOI: 10.1021/acs.jmedchem.2c01689 PMID: 36820649 PMC: PMC10009749
pubmed: 36820649
doi: 10.1021/acs.jmedchem.2c01689
pmc: PMC10009749
doi:

Substances chimiques

Palladium 5TWQ1V240M
methyl salicylate LAV5U5022Y
Metalloproteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3301-3311

Subventions

Organisme : Wellcome Trust
ID : 203149
Pays : United Kingdom

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Auteurs

Ana M Pérez-López (AM)

Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany.
Si-M/"Der Simulierte Mensch", a Science Framework of Technische Universität Berlin and Charité─Universitätsmedizin Berlin, 10623 Berlin, Germany.
ORCID: 0000-0002-3900-3335

Adam Belsom (A)

Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany.
Si-M/"Der Simulierte Mensch", a Science Framework of Technische Universität Berlin and Charité─Universitätsmedizin Berlin, 10623 Berlin, Germany.
ORCID: 0000-0002-8442-4964

Linus Fiedler (L)

Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany.
Si-M/"Der Simulierte Mensch", a Science Framework of Technische Universität Berlin and Charité─Universitätsmedizin Berlin, 10623 Berlin, Germany.
ORCID: 0000-0002-4343-6141

Xiaoyi Xin (X)

Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany.
Si-M/"Der Simulierte Mensch", a Science Framework of Technische Universität Berlin and Charité─Universitätsmedizin Berlin, 10623 Berlin, Germany.

Juri Rappsilber (J)

Chair of Bioanalytics, Technische Universität Berlin, 10623 Berlin, Germany.
Si-M/"Der Simulierte Mensch", a Science Framework of Technische Universität Berlin and Charité─Universitätsmedizin Berlin, 10623 Berlin, Germany.
Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, U.K.
ORCID: 0000-0001-5999-1310

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Dual-Bioorthogonal Catalysis by a Palladium...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Palladium › Dual-Bioorthogonal Catalysis by a Palladium...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Tumeurs de l'appareil respiratoire › Tumeurs du poumon › Tumeurs des bronches › Carcinome bronchogénique › Carcinome pulmonaire non à petites cellules › Dual-Bioorthogonal Catalysis by a Palladium...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Tumeurs de l'appareil respiratoire › Tumeurs du poumon › Dual-Bioorthogonal Catalysis by a Palladium...
questionsmedicales.fr › Phénomènes chimiques › Catalyse › Dual-Bioorthogonal Catalysis by a Palladium...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Métalloprotéines › Dual-Bioorthogonal Catalysis by a Palladium...