Chronic wound microenvironment mediates selection of biofilm-forming multi drug resistant

Staphylococcus epidermidis antimicrobial resistance biofilm chronic wounds wound healing

Journal

Research square
Titre abrégé: Res Sq
Pays: United States
ID NLM: 101768035

Informations de publication

Date de publication:
17 Feb 2023
Historique:
pubmed: 25 2 2023
medline: 25 2 2023
entrez: 24 2 2023
Statut: epublish

Résumé

Venous leg ulcers (VLU) are the most common chronic wounds characterized by bacterial biofilms and perturbed microbiome.

Identifiants

DOI: 10.21203/rs.3.rs-2562300/v1 PMID: 36824891 PMC: PMC9949177
pubmed: 36824891
doi: 10.21203/rs.3.rs-2562300/v1
pmc: PMC9949177
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIDDK NIH HHS
ID : F30 DK132806
Pays : United States

Déclaration de conflit d'intérêts

Competing Interests The Authors declare no competing financial or non-financial interests.

Auteurs

Miroslav Dinic (M)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Group for Probiotics and Microbiota-Host Interaction, Laboratory for Molecular Microbiology, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.

Rebecca Verpile (R)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Jingjing Meng (J)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Jelena Marjanovic (J)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Jamie L Burgess (JL)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Lisa Plano (L)

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.

Suzanne Hower (S)

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.

Seth R Thaller (SR)

Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Santanu Banerjee (S)

Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Hadar Lev-Tov (H)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Marjana Tomic-Canic (M)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Irena Pastar (I)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
ORCID: 0000-0003-0197-6198

Classifications MeSH