Effect of C-Type Natriuretic Peptide (CNP) on Spermatozoa Maturation in Adult Rat Epididymis.
C-type natriuretic peptide
NPR-B
acquisition of sperm motility
epididymal sperm maturation
testosterone
Journal
Current issues in molecular biology
ISSN: 1467-3045
Titre abrégé: Curr Issues Mol Biol
Pays: Switzerland
ID NLM: 100931761
Informations de publication
Date de publication:
16 02 2023
16 02 2023
Historique:
received:
30
11
2022
revised:
30
01
2023
accepted:
03
02
2023
entrez:
24
2
2023
pubmed:
25
2
2023
medline:
25
2
2023
Statut:
epublish
Résumé
C-type natriuretic peptide (CNP) is highly expressed in male reproductive tissues, such as the epididymis. The aim of this study is to explore the role of CNP in the maturation of rat epididymal spermatozoa. First, the expression levels of CNP and its specific natriuretic peptide receptor-B (NPR-B) were detected in various tissues of rats and epididymis at different stages after birth. Then a castrated rat model was established to analyze the relationship between testosterone and CNP/NPR-B expression in the epididymis. Finally, CNP and different inhibitors (NPR-B inhibitors, cGMP inhibitors) were used to incubate epididymal sperm in vitro to examine sperm mobility and expression of sperm maturation-related factors. The results showed
Identifiants
pubmed: 36826053
pii: cimb45020108
doi: 10.3390/cimb45020108
pmc: PMC9955803
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1681-1692Subventions
Organisme : National Natural Science Foundation of China
ID : No. 81771575
Organisme : Guangdong Basic and Applied Basic Research Foundation
ID : 2021A1515220178
Références
Sci Transl Med. 2014 Aug 13;6(249):249ra108
pubmed: 25122636
Reprod Biol Endocrinol. 2014 Jul 10;12:64
pubmed: 25012822
Andrologia. 2021 Apr;53(3):e13989
pubmed: 33491190
BMC Biol. 2020 Aug 19;18(1):103
pubmed: 32814578
Reproduction. 2019 Nov;158(5):R155-R167
pubmed: 31176304
Reprod Biomed Online. 2019 Mar;38(3):289-299
pubmed: 30655075
Mol Cell Endocrinol. 2012 Feb 26;349(2):145-53
pubmed: 21996373
Biol Reprod. 2004 Feb;70(2):290-6
pubmed: 14522836
World J Mens Health. 2019 May;37(2):186-198
pubmed: 30358184
Front Cell Dev Biol. 2019 Dec 18;7:341
pubmed: 31921853
Clin Chem. 2005 Nov;51(11):2173-6
pubmed: 16244294
Biol Reprod. 1990 Jul;43(1):113-20
pubmed: 2393684
Hum Exp Toxicol. 2021 Dec;40(12):2025-2038
pubmed: 34085563
Asian J Androl. 2016 Jan-Feb;18(1):80-4
pubmed: 25926602
Science. 2001 Mar 2;291(5509):1783-5
pubmed: 11230693
Acta Biochim Pol. 2021 Jul 8;68(4):603-609
pubmed: 34237204
Biochem Biophys Res Commun. 1990 Apr 30;168(2):863-70
pubmed: 2139780
Mol Cell Endocrinol. 2014 Jan 25;382(1):234-243
pubmed: 24099862
Science. 2010 Oct 15;330(6002):366-9
pubmed: 20947764
Int J Androl. 2008 Aug;31(4):427-37
pubmed: 17822422
Biol Reprod. 2000 Aug;63(2):368-76
pubmed: 10906039
Sci Rep. 2015 Oct 23;5:15639
pubmed: 26492952
J Androl. 2011 Nov-Dec;32(6):651-64
pubmed: 21764898
Gen Comp Endocrinol. 2000 Apr;118(1):26-38
pubmed: 10753564
Endocrinology. 1993 Nov;133(5):2141-9
pubmed: 8404664
Reprod Biol Endocrinol. 2011 Jun 30;9:96
pubmed: 21718510
Mol Hum Reprod. 2016 Feb;22(2):69-82
pubmed: 26612782
Sci Rep. 2017 Jan 05;7:39711
pubmed: 28054671
Hum Reprod. 2022 Apr 1;37(4):651-668
pubmed: 35137089
Theriogenology. 2019 Nov;139:132-146
pubmed: 31404823
Andrologia. 2019 Nov;51(10):e13387
pubmed: 31661170
Hum Reprod Update. 2021 Dec 21;28(1):51-66
pubmed: 34618012
BMC Genomics. 2006 Dec 13;7:314
pubmed: 17166261
Rev Int Androl. 2022 Oct-Dec;20(4):240-248
pubmed: 35933293
Hum Reprod Update. 2016 Sep;22(5):574-87
pubmed: 27307387
Regul Pept. 2008 Feb 7;146(1-3):204-12
pubmed: 17928074
J Clin Endocrinol Metab. 2007 Nov;92(11):4294-8
pubmed: 17684048
Int J Mol Sci. 2022 Sep 08;23(18):
pubmed: 36142279
Reprod Biol Endocrinol. 2013 Jul 01;11:59
pubmed: 23815807
Int J Androl. 1999 Jun;22(3):197-207
pubmed: 10367241
Clin Sci (Lond). 2018 May 8;132(9):905-908
pubmed: 29739821
J Biol Chem. 1993 Feb 15;268(5):3698-703
pubmed: 8094083
Hum Reprod Update. 2012 Jul;18(4):420-35
pubmed: 22523110
Cell Discov. 2021 May 18;7(1):34
pubmed: 34001862
Mol Cell Endocrinol. 2016 May 15;427:143-54
pubmed: 26987518
Biol Reprod. 2007 Jan;76(1):63-73
pubmed: 17005942
Mol Reprod Dev. 2000 Jun;56(2):180-8
pubmed: 10813850
PLoS Biol. 2020 Jul 14;18(7):e3000410
pubmed: 32663219
Asian J Androl. 2007 Jul;9(4):515-21
pubmed: 17589789
Cell Mol Life Sci. 2011 Feb;68(4):697-708
pubmed: 20694738
Biol Reprod. 2011 Jun;84(6):1282-91
pubmed: 21311037
Asian J Androl. 2016 Jan-Feb;18(1):3-9
pubmed: 26585699