Xylan-Porphyrin Hydrogels as Light-Triggered Gram-Positive Antibacterial Agents.
Gram-positive bacteria
hydrogel
photodynamic antimicrobial therapy
photosensitizers
porphyrins
xylan
Journal
Gels (Basel, Switzerland)
ISSN: 2310-2861
Titre abrégé: Gels
Pays: Switzerland
ID NLM: 101696925
Informations de publication
Date de publication:
02 Feb 2023
02 Feb 2023
Historique:
received:
23
12
2022
revised:
29
01
2023
accepted:
31
01
2023
entrez:
24
2
2023
pubmed:
25
2
2023
medline:
25
2
2023
Statut:
epublish
Résumé
In the present work, we report on the synthesis of light-triggered antibacterial hydrogels, based on xylan chains covalently bound to meso-tetra(4-carboxyphenyl)porphyrin (TCPP). Not only does TCPP act as a photosensitizer efficient against Gram-positive bacteria, but it also serves as a cross-linking gelator, enabling the simple and easy building of xylan conjugate hydrogels. The hydrogels were characterized by infrared spectroscopy (ATR-FTIR), scanning electron microscopy (SEM), along with swelling and rheological tests. The antimicrobial activity of the hydrogels was tested under visible light irradiation against two Gram-positive bacterial strains,
Identifiants
pubmed: 36826294
pii: gels9020124
doi: 10.3390/gels9020124
pmc: PMC9957218
pii:
doi:
Types de publication
Journal Article
Langues
eng
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