Drug-Coated Balloon vs. Drug-Eluting Stents for De Novo Unprotected Left Main Stem Disease: The SPARTAN-LMS Study.
complex coronary intervention
drug-coated balloon
drug-eluting stent
left main stem
Journal
Journal of cardiovascular development and disease
ISSN: 2308-3425
Titre abrégé: J Cardiovasc Dev Dis
Pays: Switzerland
ID NLM: 101651414
Informations de publication
Date de publication:
16 Feb 2023
16 Feb 2023
Historique:
received:
23
01
2023
revised:
10
02
2023
accepted:
14
02
2023
entrez:
24
2
2023
pubmed:
25
2
2023
medline:
25
2
2023
Statut:
epublish
Résumé
The objective of this study is to compare the outcomes of patients treated with drug-coated balloons (DCBs) or second-generation drug-eluting stents (DESs) for de novo unprotected left main stem (LMS) disease. Previous studies comparing the treatment of LMS disease suggest that the mortality for DES PCI is not worse than CABG. There are limited data from studies investigating the treatment of de novo LMS disease with DCB angioplasty. We compared the all-cause and cardiac mortality of patients treated with paclitaxel DCB to those with second-generation DES for de novo LMS disease from July 2014 to November 2019. Data were analysed using Kaplan-Meier analyses and propensity-matched analyses. A total of 148 patients were treated with either a DCB or DES strategy. There was no significant difference in all-cause mortality in the DCB group (19.5%) compared to the DES group (15.9%) (HR 1.42 [0.61-3.32],
Identifiants
pubmed: 36826580
pii: jcdd10020084
doi: 10.3390/jcdd10020084
pmc: PMC9963161
pii:
doi:
Types de publication
Journal Article
Langues
eng
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