Social disparities in pain management provision in stage IV lung cancer: A national registry analysis.
Journal
Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R
Informations de publication
Date de publication:
22 Feb 2023
22 Feb 2023
Historique:
entrez:
24
2
2023
pubmed:
25
2
2023
medline:
3
3
2023
Statut:
ppublish
Résumé
A strong association exists between pain and lung cancer (LC). Focusing on the disparities in pain referral in LC patients, we are aiming to characterize the prevalence and patterns of referrals to pain management (PM) in Stage IV non-small-cell LC (NSLC) and small-cell LC (SCLC). We sampled the National Cancer Database for de novo stage IV LC (2004-2016). We analyzed trends of pain referral using the Cochran-Armitage test. Chi-squared statistics were used to identify the sociodemographic and clinico-pathologic determinants of referral to PM, and significant variables (P < .05) were included in one multivariable regression model predicting the likelihood of pain referral. A total N = 17,620 (3.1%) of NSLC and N = 4305 (2.9%) SCLC patients were referred to PM. A significant increase in referrals was observed between 2004 and 2016 (NSLC: 1.7%-4.1%, P < .001; SCLC: 1.6%-4.2%, P < .001). Patient and disease factors played a significant role in likelihood of referral in both groups. Demographic factors such as gender, age, and facility type played a role in the likelihood of pain referrals, highlighting the gap and need for multidisciplinary PM in patients with LC. Despite an increase in the proportion of referrals to PM issued for terminal stage LC, the overall proportion remains low. To ensure better of quality of life for patients, oncologists need to be made aware of existent disparities and implicit biases.
Identifiants
pubmed: 36827013
doi: 10.1097/MD.0000000000032888
pii: 00005792-202302220-00013
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e32888Informations de copyright
Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to disclose.
Références
Te Boveldt N, Vernooij-Dassen M, Burger N, et al. Pain and its interference with daily activities in medical oncology outpatients. Pain Physician. 2013;16:379–89.
Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2019. CA Cancer J Clin. 2019;69:7–34.
Advani S, Zhang D, Tammemagi M, et al. Comorbidity profiles and lung cancer screening among older adults: US behavioral risk factor surveillance system 2017 to 2019. Ann Am Thorac Soc. 2021;18:1886–93.
SEER*Explorer: An interactive website for SEER cancer statistics [Internet]. Available at: https://seer.cancer.gov/explorer/ [access date July 2021].
Cooley ME. Symptoms in adults with lung cancer: a systematic research review. J Pain Symptom Manage. 2000;19:137–53.
Mercadante S, Vitrano V. Pain in patients with lung cancer: pathophysiology and treatment. Lung Cancer. 2010;68:10–5.
Grippi MA. Clinical aspects of lung cancer. Semin Roentgenol. 1990;25:12–24.
Greenwald HP, Bonica JJ, Bergner M. The prevalence of pain in four cancers. Cancer. 1987;60:2563–9.
Caraceni A, Portenoy RK. An international survey of cancer pain characteristics and syndromes. Pain. 1999;82:263–74.
Brescia FJ, Adler D, Gray G, et al. Hospitalized advanced cancer patients: a profile. J Pain Symptom Manage. 1990;5:221–7.
Grond S, Zech D, Diefenbach C, et al. Assessment of cancer pain: a prospective evaluation in 2266 cancer patients referred to a pain service. Pain. 1996;64:107–14.
Benveniste MF, Gomez D, Carter BW, et al. Recognizing radiation therapy–related complications in the chest. Radiographics. 2019;39:344–66.
Zajączkowska R, Kocot-Kępska M, Leppert W, et al. Mechanisms of chemotherapy-induced peripheral neuropathy. Int J Mol Sci. 2019;20:1451.
Staff NP, Grisold A, Grisold W, et al. Chemotherapy-induced peripheral neuropathy: a current review. Ann Neurol. 2017;81:772–81.
Vander Els NJ, Stover DE. Chemotherapy-induced lung disease. Clin Pulm Med. 2004;11:84–91.
Mossey JM. Defining racial and ethnic disparities in pain management. Clin Orthop Relat Res. 2011;469:1859–70.
Cykert S, Eng E, Walker P, et al. A system-based intervention to reduce Black-White disparities in the treatment of early stage lung cancer: a pragmatic trial at five cancer centers. Cancer Med. 2019;8:1095–102.
Scott-Warren J, Bhaskar A. Cancer pain management: part II: interventional techniques. Contin Educ Anaesth Crit Care Pain. 2015;15:68–72.
Swarm RA, Paice JA, Anghelescu DL, et al. Adult cancer pain, version 3.2019, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2019;17:977–1007.
Bach PB, Cramer LD, Warren JL, et al. Racial differences in the treatment of early-stage lung cancer. N Engl J Med. 1999;341:1198–205.
Opioid Crisis Statistics. 2021; Available at: https://www.hhs.gov/opioids/about-the-epidemic/opioid-crisis-statistics/index.html# [access date July 2021].
Pergolizzi J, Raffa RB. Common opioid-drug interactions: what clinicians need to know. Pract Pain Manage. 2017;12:1–3.
Simoff MJ, Lally B, Slade MG, et al. Symptom management in patients with lung cancer: diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013;143:e455S–97S.
NCCN Guidelines Version 2.2021: Adult Cancer Pain. 2021 06/03/2021 10/04/2021].
Anekar AA, Cascella M. – StatPearls [Internet]. 2021.
Lau J, Flamer D, Murphy-Kane P. Interventional anesthesia and palliative care collaboration to manage cancer pain: a narrative review. Can J Anesth. 2020;67:235–46.
Sloan PA. The evolving role of interventional pain management in oncology. J Support Oncol. 2004;2:491–500, 503.
Bilimoria KY, Stewart AK, Winchester DP, et al. The National Cancer Data Base: a powerful initiative to improve cancer care in the United States. Ann Surg Oncol. 2008;15:683–90.
Simmons CP, MacLeod N, Laird BJ. Clinical management of pain in advanced lung cancer. Clin Med Insights Oncol. 2012;6:CMO.S8360.
Crul BJ, Blok LM, van Egmond J, et al. The present role of percutaneous cervical cordotomy for the treatment of cancer pain. J Headache Pain. 2005;6:24–9.
Patt R, Reddy S. Spinal neurolysis for cancer pain: indications and recent results. Ann Acad Med Singapore. 1994;23:216–20.
Myers DP, Lema MJ, de Leon-Casasola OA, et al. Interpleural analgesia for the treatment of severe cancer pain in terminally ill patients. J Pain Symptom Manage. 1993;8:505–10.
Anderson KO, Green CR, Payne R. Racial and ethnic disparities in pain: causes and consequences of unequal care. J Pain. 2009;10:1187–204.
Landon BE, Onnela J-P, Meneades L, et al. Assessment of racial disparities in primary care physician specialty referrals. JAMA Netw Open. 2021;4:e2029238–e2029238.
Wang XS, Fairclough DL, Liao Z, et al. Longitudinal study of the relationship between chemoradiation therapy for non–small-cell lung cancer and patient symptoms. J Clin Oncol. 2006;24:4485–91.
Cohen E, Botti M, Hanna B, et al. Pain beliefs and pain management of oncology patients. Cancer Nurs. 2008;31:E1–8.
Jho HJ, Kim Y, Kong KA, et al. Knowledge, practices, and perceived barriers regarding cancer pain management among physicians and nurses in Korea: a nationwide multicenter survey. PLoS One. 2014;9:e105900.
Canivet D, Delvaux N, Gibon A-S, et al. Improving communication in cancer pain management nursing: a randomized controlled study assessing the efficacy of a communication skills training program. Support Care Cancer. 2014;22:3311–20.
Glare PA, Davies PS, Finlay E, et al. Pain in cancer survivors. J Clin Oncol. 2014;32:1739.
O’Connor L, Hassett A, Sheridan N. Pain assessment and registration in medical oncology clinics: operationalised through the lens of health care professionals and patients. HRB Open Res. 2021;4:86.