Ertapenem Supplemented Selective Media as a New Strategy to Distinguish β-Lactam-Resistant Enterobacterales: Application to Clinical and Wastewater Samples.
New Caledonia
antimicrobial resistance
carbapenemase-producing-carbapenem-resistant-enterobacterales
culture-based approach
ertapenem
wastewater
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
15 Feb 2023
15 Feb 2023
Historique:
received:
05
01
2023
revised:
03
02
2023
accepted:
09
02
2023
entrez:
25
2
2023
pubmed:
26
2
2023
medline:
26
2
2023
Statut:
epublish
Résumé
The increase in carbapenem-resistant Enterobacterales (CRE) is mostly driven by the spread of carbapenemase-producing (CP) strains. In New Caledonia, the majority of carbapenemases found are IMP-type carbapenemases that are difficult to detect on routine selective media. In this study, a culture-based method with ertapenem selection is proposed to distinguish non-CRE, non-CP-CRE, and CP-CRE from samples with very high bacterial loads. Firstly, assays were carried out with phenotypically well-characterized β-lactam-resistant Enterobacterales isolates. Then, this approach was applied to clinical and environmental samples. Presumptive CP-CRE isolates were finally identified, and the presence of a carbapenemase was assessed. In a collection of 27 phenotypically well-characterized β-lactam-resistant Enterobacterales, an ertapenem concentration of 0.5 µg·mL
Identifiants
pubmed: 36830303
pii: antibiotics12020392
doi: 10.3390/antibiotics12020392
pmc: PMC9952050
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : CRESICA
ID : ARCANE Project
Références
Sci Total Environ. 2019 Jul 1;672:618-624
pubmed: 30974353
J Glob Antimicrob Resist. 2020 Jun;21:91-98
pubmed: 31627023
Lancet. 2022 Feb 12;399(10325):629-655
pubmed: 35065702
Euro Surveill. 2015;20(45):
pubmed: 26675038
Antibiotics (Basel). 2020 Mar 31;9(4):
pubmed: 32244420
Med Sci (Basel). 2017 Dec 21;6(1):
pubmed: 29267233
Western Pac Surveill Response J. 2020 Feb 20;11(1):41-46
pubmed: 32963890
Antimicrob Agents Chemother. 2004 Jan;48(1):15-22
pubmed: 14693513
Front Microbiol. 2021 Jan 15;11:609856
pubmed: 33519761
Antibiotics (Basel). 2022 Jul 08;11(7):
pubmed: 35884172
J Clin Microbiol. 2020 Oct 21;58(11):
pubmed: 32878951
J Clin Microbiol. 2007 Feb;45(2):501-5
pubmed: 17182756
Diagn Microbiol Infect Dis. 2013 Feb;75(2):214-7
pubmed: 23142168
Antibiotics (Basel). 2022 Feb 11;11(2):
pubmed: 35203838
Diagn Microbiol Infect Dis. 2018 Feb;90(2):77-80
pubmed: 29150373
J Clin Microbiol. 2001 Aug;39(8):2964-6
pubmed: 11474023
Infect Dis Now. 2022 Feb;52(1):7-12
pubmed: 34487876
J Hosp Infect. 2016 Aug;93(4):395-402
pubmed: 26944903
J Clin Microbiol. 2020 Jun 24;58(7):
pubmed: 32376668
Antimicrob Agents Chemother. 2016 Sep 23;60(10):6425-9
pubmed: 27503655
Clin Microbiol Rev. 2007 Jul;20(3):440-58, table of contents
pubmed: 17630334
Int J Infect Dis. 2017 Sep;62:39-43
pubmed: 28610832
Curr Drug Targets. 2016;17(9):1006-28
pubmed: 26960341
PLoS One. 2016 Apr 22;11(4):e0154092
pubmed: 27104910
J Microbiol Methods. 2018 Oct;153:40-44
pubmed: 30189222
Nat Microbiol. 2019 Sep;4(9):1432-1442
pubmed: 31439928
Expert Rev Anti Infect Ther. 2016;14(1):95-108
pubmed: 26535959
Water Res. 2019 Sep 15;161:232-241
pubmed: 31202110
Int J Antimicrob Agents. 2015 Feb;45(2):130-6
pubmed: 25465526
FEMS Microbiol Rev. 2018 Jan 1;42(1):
pubmed: 29069382
Sci Total Environ. 2022 Feb 1;806(Pt 4):151339
pubmed: 34740643
Clin Infect Dis. 2017 Feb 1;64(3):257-264
pubmed: 28013264
Antimicrob Agents Chemother. 2004 Dec;48(12):4793-9
pubmed: 15561858
Nature. 2017 Feb 28;543(7643):15
pubmed: 28252092
J Antimicrob Chemother. 2017 Jan;72(1):166-171
pubmed: 27703058
Antibiotics (Basel). 2019 Mar 19;8(1):
pubmed: 30893880
J Microbiol Methods. 2016 May;124:10-2
pubmed: 26945518
Front Microbiol. 2022 Dec 15;13:977106
pubmed: 36590429
Antimicrob Agents Chemother. 2003 Dec;47(12):3881-9
pubmed: 14638498
BMJ Glob Health. 2020 Apr;5(4):
pubmed: 32349993
J Antimicrob Chemother. 2020 Apr 1;75(4):873-882
pubmed: 31960024