Epigenetic Mechanisms and Nephrotic Syndrome: A Systematic Review.
DNA methylation
FSGS
SRNS
SSNS
epigenetics
histone modification
long non-coding RNA
micro-RNA
minimal change disease
nephrotic syndrome
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
10 Feb 2023
10 Feb 2023
Historique:
received:
13
01
2023
revised:
30
01
2023
accepted:
01
02
2023
entrez:
25
2
2023
pubmed:
26
2
2023
medline:
26
2
2023
Statut:
epublish
Résumé
A small subset of people with nephrotic syndrome (NS) have genetically driven disease. However, the disease mechanisms for the remaining majority are unknown. Epigenetic marks are reversible but stable regulators of gene expression with utility as biomarkers and therapeutic targets. We aimed to identify and assess all published human studies of epigenetic mechanisms in NS. PubMed (MEDLINE) and Embase were searched for original research articles examining any epigenetic mechanism in samples collected from people with steroid resistant NS, steroid sensitive NS, focal segmental glomerulosclerosis or minimal change disease. Study quality was assessed by using the Joanna Briggs Institute critical appraisal tools. Forty-nine studies met our inclusion criteria. The majority of these examined micro-RNAs (
Identifiants
pubmed: 36831050
pii: biomedicines11020514
doi: 10.3390/biomedicines11020514
pmc: PMC9953384
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Medical Research Council
ID : MR/P024297/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R013942/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/W000105/1
Pays : United Kingdom
Références
Pediatr Res. 2008 Dec;64(6):637-42
pubmed: 18679168
Transl Androl Urol. 2020 Oct;9(5):2235-2241
pubmed: 33209688
Clin Chem. 2013 Apr;59(4):658-66
pubmed: 23344497
PeerJ. 2015 Jun 02;3:e990
pubmed: 26056621
J Transl Med. 2018 Apr 10;16(1):91
pubmed: 29636065
Aging Cell. 2015 Dec;14(6):924-32
pubmed: 25913071
Mol Immunol. 2022 Jan;141:21-32
pubmed: 34785326
Nat Genet. 2015 Jun;47(6):607-14
pubmed: 25938942
Lancet. 2003 Aug 23;362(9384):629-39
pubmed: 12944064
J Am Soc Nephrol. 2017 Oct;28(10):2985-2992
pubmed: 28663230
BMC Nephrol. 2019 Aug 27;20(1):336
pubmed: 31455266
Kidney Int. 2017 Oct;92(4):836-849
pubmed: 28476557
Clin Chim Acta. 2013 Mar 15;418:5-11
pubmed: 23313053
Med Sci Monit. 2020 Jun 03;26:e922090
pubmed: 32489187
Int J Mol Med. 2015 Sep;36(3):669-77
pubmed: 26134897
J Biol Chem. 2018 Dec 28;293(52):20227-20239
pubmed: 30389788
Sci Rep. 2019 Jan 24;9(1):716
pubmed: 30679767
Sci Rep. 2019 Aug 19;9(1):11960
pubmed: 31427598
Pediatr Nephrol. 2009 Sep;24(9):1691-8
pubmed: 19495805
EBioMedicine. 2019 Jan;39:552-561
pubmed: 30467011
Kidney Int. 2017 Apr;91(4):937-947
pubmed: 28117080
Exp Mol Pathol. 2015 Dec;99(3):590-5
pubmed: 26481277
Kidney Int. 2022 Apr;101(4):766-778
pubmed: 35114200
Clin Exp Nephrol. 2014 Oct;18(5):711-7
pubmed: 24198052
J Transl Med. 2021 Mar 30;19(1):130
pubmed: 33785019
Clin Transl Sci. 2021 May;14(3):964-975
pubmed: 33382913
J Am Soc Nephrol. 2014 Jan;25(1):92-104
pubmed: 24029422
Biomed Res Int. 2017;2017:9531074
pubmed: 28299339
Biomed Res Int. 2017;2017:2168767
pubmed: 29214160
J Pathol. 2013 Apr;229(5):660-71
pubmed: 23436459
J Am Soc Nephrol. 2005 Mar;16(3):629-37
pubmed: 15659563
PeerJ. 2020 Dec 16;8:e10377
pubmed: 33362958
Sci Rep. 2018 Jul 18;8(1):10875
pubmed: 30022109
Folia Histochem Cytobiol. 2011;49(4):719-28
pubmed: 22252769
Kidney Int. 2013 Apr;83(4):749-56
pubmed: 23325076
Lancet. 2014 Oct 4;384(9950):1273-81
pubmed: 24965823
Biomed Rep. 2021 Jan;14(1):17
pubmed: 33365127
Int J Nephrol Renovasc Dis. 2020 Aug 10;13:193-201
pubmed: 32848442
Clin J Am Soc Nephrol. 2014 Sep 5;9(9):1545-52
pubmed: 25107948
BMC Genomics. 2019 Jun 21;20(1):513
pubmed: 31226924
Int J Mol Med. 2017 Nov;40(5):1511-1519
pubmed: 28949388
J Clin Invest. 2018 Jan 2;128(1):483-499
pubmed: 29227285
Biomed Res Int. 2017;2017:7298160
pubmed: 28246603
Nat Rev Genet. 2019 Feb;20(2):109-127
pubmed: 30479381
BMC Res Notes. 2017 Sep 15;10(1):480
pubmed: 28915836
Biofactors. 2020 Jul;46(4):645-652
pubmed: 32412691
Am J Kidney Dis. 2015 Feb;65(2):223-32
pubmed: 25218681
Acta Biochim Pol. 2016;63(1):131-138
pubmed: 26828667
Int J Clin Exp Pathol. 2015 Jun 01;8(6):7282-6
pubmed: 26261628
Front Cell Dev Biol. 2021 Oct 11;9:727370
pubmed: 34708038
Exp Ther Med. 2021 Jun;21(6):620
pubmed: 33936277
Eur J Clin Invest. 2015 Apr;45(4):394-404
pubmed: 25682967
Front Pediatr. 2021 Apr 21;9:651544
pubmed: 33968853
Biochem Biophys Res Commun. 2020 Oct 20;531(3):341-349
pubmed: 32800553
Biofactors. 2020 Nov;46(6):995-1005
pubmed: 33031585
Bioinformatics. 2019 Feb 15;35(4):560-570
pubmed: 30084929
Cell Death Dis. 2018 May 10;9(5):533
pubmed: 29748623
Pediatr Nephrol. 2012 Dec;27(12):2233-41
pubmed: 22855301
Nat Med. 2013 Apr;19(4):481-7
pubmed: 23502960
Brain Tumor Res Treat. 2022 Apr;10(2):83-93
pubmed: 35545827
P T. 2016 May;41(5):296-300
pubmed: 27162469
Expert Opin Drug Discov. 2020 Sep;15(9):987-992
pubmed: 32421364
Am J Nephrol. 2009;30(6):505-13
pubmed: 19797895
Int J Mol Sci. 2015 Oct 12;16(10):24032-47
pubmed: 26473838
Iran J Kidney Dis. 2014 Sep;8(5):371-6
pubmed: 25194403
PLoS One. 2012;7(12):e51140
pubmed: 23272089
Nucleic Acids Res. 2011 Jul;39(13):5692-703
pubmed: 21447562