IKAROS in Acute Leukemia: A Positive Influencer or a Mean Hater?
IKZF1
acute lymphoblastic leukemia
acute myeloid leukemia
leukemogenesis
molecular pathways
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
07 Feb 2023
07 Feb 2023
Historique:
received:
06
12
2022
revised:
31
01
2023
accepted:
04
02
2023
entrez:
25
2
2023
pubmed:
26
2
2023
medline:
3
3
2023
Statut:
epublish
Résumé
One key process that controls leukemogenesis is the regulation of oncogenic gene expression by transcription factors acting as tumor suppressors. Understanding this intricate mechanism is crucial to elucidating leukemia pathophysiology and discovering new targeted treatments. In this review, we make a brief overview of the physiological role of IKAROS and the molecular pathway that contributes to acute leukemia pathogenesis through
Identifiants
pubmed: 36834692
pii: ijms24043282
doi: 10.3390/ijms24043282
pmc: PMC9961161
pii:
doi:
Substances chimiques
Ikaros Transcription Factor
148971-36-2
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Oncogene. 2006 Feb 16;25(7):1118-24
pubmed: 16205638
Acta Pharm Sin B. 2016 Nov;6(6):513-521
pubmed: 27818917
Mol Immunol. 2011 May;48(9-10):1272-8
pubmed: 21477865
Nat Genet. 2009 Sep;41(9):1001-5
pubmed: 19684603
Leukemia. 2016 Jun;30(6):1436-40
pubmed: 26639180
Leukemia. 2016 Jan;30(1):32-8
pubmed: 26202931
Int J Mol Sci. 2020 Mar 03;21(5):
pubmed: 32138279
Blood. 2013 Mar 7;121(10):1769-82
pubmed: 23303821
Cell. 1995 Oct 20;83(2):289-99
pubmed: 7585946
Blood Rev. 2020 Nov;44:100677
pubmed: 32245541
Cancer Cell. 2013 Sep 9;24(3):282-4
pubmed: 24029225
Nat Immunol. 2014 Mar;15(3):294-304
pubmed: 24509510
Leukemia. 2015 Nov;29(11):2154-61
pubmed: 26050650
Mol Cell Biol. 2006 Jan;26(1):209-20
pubmed: 16354692
Leukemia. 2014 Feb;28(2):302-10
pubmed: 23823658
J Immunol. 2015 May 15;194(10):4698-704
pubmed: 25870237
J Biol Chem. 2008 Mar 28;283(13):8291-300
pubmed: 18223295
World J Biol Chem. 2011 Jun 26;2(6):126-31
pubmed: 21765978
Epigenomics. 2018 Jan;10(1):59-69
pubmed: 28994305
J Exp Med. 2013 Dec 16;210(13):2823-32
pubmed: 24297995
Blood. 2013 Mar 28;121(13):2440-51
pubmed: 23335373
Nat Commun. 2016 Jun 06;7:11790
pubmed: 27265895
Nature. 2010 Dec 2;468(7324):701-4
pubmed: 21124456
J Biol Chem. 2016 Apr 22;291(17):9073-86
pubmed: 26841869
Genes Dev. 2001 Jul 15;15(14):1817-32
pubmed: 11459831
Leukemia. 2017 Aug;31(8):1661-1670
pubmed: 28484264
Nature. 2008 May 1;453(7191):110-4
pubmed: 18408710
J Biol Chem. 2013 Dec 6;288(49):35170-9
pubmed: 24145030
Blood. 2011 Jul 7;118(1):167-76
pubmed: 21531982
Eur J Immunol. 2019 Sep;49(9):1344-1355
pubmed: 31151137
Int J Mol Sci. 2020 Feb 18;21(4):
pubmed: 32085659
Exp Hematol. 2017 Feb;46:1-8
pubmed: 27865806
Sci Rep. 2016 Nov 25;6:38004
pubmed: 27885263
Haematologica. 2015 Sep;100(9):1151-9
pubmed: 26069293
Development. 2005 Apr;132(8):1751-62
pubmed: 15790962
Hematology Am Soc Hematol Educ Program. 2012;2012:129-36
pubmed: 23233571
Cell Mol Life Sci. 2008 Oct;65(20):3290-303
pubmed: 18818879
Clin Cancer Res. 2007 Feb 1;13(3):1019-28
pubmed: 17289898
Nat Immunol. 2017 Jun;18(6):694-704
pubmed: 28369050
J Exp Med. 2011 Oct 24;208(11):2163-74
pubmed: 21911423
Oncotarget. 2015 Dec 8;6(39):42300-11
pubmed: 26517351
Oncotarget. 2016 Aug 2;7(31):49722-49732
pubmed: 27391346
Oncogenesis. 2018 Nov 12;7(11):84
pubmed: 30420689
Mol Cell Biol. 1994 Dec;14(12):8292-303
pubmed: 7969165
Adv Biol Regul. 2020 Jan;75:100665
pubmed: 31623972
Blood. 2007 Jun 1;109(11):4641-7
pubmed: 17299091
Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):602-7
pubmed: 11805317
Science. 2008 Nov 28;322(5906):1377-80
pubmed: 19039135
Haematologica. 2013 Apr;98(4):597-601
pubmed: 23065506
Blood. 2014 Jul 3;124(1):106-10
pubmed: 24787007
Blood. 2010 Dec 23;116(26):5961-71
pubmed: 20870899
J Clin Oncol. 2018 Apr 20;36(12):1240-1249
pubmed: 29498923
Eur J Immunol. 2006 Mar;36(3):516-25
pubmed: 16482514
Mol Cell. 2003 Feb;11(2):459-70
pubmed: 12620233
Int J Biochem Cell Biol. 2002 Oct;34(10):1304-7
pubmed: 12127581
J Exp Med. 2017 Mar 6;214(3):793-814
pubmed: 28190001
Haematologica. 2013 Jul;98(7):1081-8
pubmed: 23508010
Genome Res. 2001 Aug;11(8):1327-34
pubmed: 11483573
Nat Med. 2013 Aug;19(8):1014-22
pubmed: 23852341
J Biol Chem. 2009 May 15;284(20):13869-13880
pubmed: 19282287
Curr Opin Immunol. 2018 Apr;51:14-23
pubmed: 29278858
Leuk Lymphoma. 2015 Mar;56(3):814-6
pubmed: 25005032
Semin Hematol. 2009 Jan;46(1):3-15
pubmed: 19100363
Genes Immun. 2012 Jul;13(5):421-30
pubmed: 22535200
Blood. 2013 Oct 10;122(15):2572-81
pubmed: 23990620
Nat Immunol. 2013 Oct;14(10):1073-83
pubmed: 24013668
EMBO J. 1996 Oct 1;15(19):5358-69
pubmed: 8895580
Science. 1992 Oct 30;258(5083):808-12
pubmed: 1439790
Nature. 2004 Jun 3;429(6991):566-71
pubmed: 15152264
J Exp Med. 1999 Oct 18;190(8):1039-48
pubmed: 10523602
Blood Adv. 2017 Aug 30;1(20):1657-1671
pubmed: 29296813
Blood. 2003 Mar 15;101(6):2219-26
pubmed: 12406904
Semin Cancer Biol. 2019 Aug;57:79-85
pubmed: 30448242
Mol Cell Biochem. 2011 Oct;356(1-2):201-7
pubmed: 21750978
Mol Cell Biol. 1994 Nov;14(11):7111-23
pubmed: 7935426
Nature. 2007 Apr 12;446(7137):758-64
pubmed: 17344859
J Mol Med (Berl). 2016 Dec;94(12):1327-1334
pubmed: 27492707
Eur Rev Med Pharmacol Sci. 2018 Aug;22(16):5240-5247
pubmed: 30178847
Exp Mol Med. 2019 Jan 11;51(1):1-15
pubmed: 30635552
Annu Rev Immunol. 1997;15:155-76
pubmed: 9143685
Nature. 2018 Oct;562(7727):373-379
pubmed: 30209392
Eur J Med Chem. 2019 Jan 1;161:131-140
pubmed: 30343192
J Biol Chem. 2002 Apr 12;277(15):13007-15
pubmed: 11799125
Nat Immunol. 2019 Nov;20(11):1517-1529
pubmed: 31591571
Histol Histopathol. 2009 Nov;24(11):1451-61
pubmed: 19760594
Cancer Manag Res. 2019 May 02;11:3933-3943
pubmed: 31118806
Leuk Lymphoma. 2019 Mar;60(3):829-832
pubmed: 30188230
Leukemia. 2013 Feb;27(2):409-15
pubmed: 22858985
Oncotarget. 2017 Jan 31;8(5):8022-8034
pubmed: 28030830
Trends Immunol. 2014 Mar;35(3):131-7
pubmed: 24332591
Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11711-E11720
pubmed: 30487223
Nat Rev Immunol. 2002 Mar;2(3):162-74
pubmed: 11913067
Blood. 2009 Sep 3;114(10):2159-67
pubmed: 19589926
J Exp Med. 2017 Mar 6;214(3):773-791
pubmed: 28190000
J Cancer. 2019 Jun 9;10(16):3842-3850
pubmed: 31333801
Int J Mol Sci. 2021 Jan 22;22(3):
pubmed: 33499314
Cancer Cell. 2015 Sep 14;28(3):343-56
pubmed: 26321221
Am J Respir Crit Care Med. 2020 Mar 1;201(5):610-613
pubmed: 31661301
J Exp Med. 2009 Aug 3;206(8):1739-53
pubmed: 19620627
Eur J Haematol. 2013 Sep;91(3):201-208
pubmed: 23751147
Blood. 2008 Feb 1;111(3):1138-46
pubmed: 17934067
Nat Immunol. 2014 Mar;15(3):283-93
pubmed: 24509509
Nat Cell Biol. 2011 Jun;13(6):668-75
pubmed: 21532585
Biochem Biophys Res Commun. 2016 Nov 18;480(3):409-414
pubmed: 27771248
Haematologica. 2019 Jul;104(7):1396-1406
pubmed: 30630978
Elife. 2017 Mar 20;6:
pubmed: 28318487
BMC Mol Biol. 2009 Jan 21;10:2
pubmed: 19159451
Nature. 2018 Oct;562(7728):526-531
pubmed: 30333627
Am J Hematol. 2012 Nov;87(11):1010-6
pubmed: 22887079
Blood Res. 2019 Jun;54(2):144-148
pubmed: 31309094
J Clin Oncol. 2009 Nov 1;27(31):5202-7
pubmed: 19770381
Front Immunol. 2019 Jun 06;10:1299
pubmed: 31244845
Leukemia. 2013 Feb;27(2):503-7
pubmed: 22868967
Leukemia. 2014 Jan;28(1):70-7
pubmed: 24064621
Biochem Biophys Res Commun. 2003 Jan 10;300(2):391-6
pubmed: 12504096
PLoS Genet. 2018 Jul 12;14(7):e1007485
pubmed: 30001316
Adv Biol Regul. 2017 Aug;65:16-25
pubmed: 28623166
Genes Dev. 2017 Dec 1;31(23-24):2343-2360
pubmed: 29326336
PLoS One. 2013 Aug 19;8(8):e71302
pubmed: 23977012
Leukemia. 2013 Mar;27(3):746-8
pubmed: 22922568
Biochem Biophys Res Commun. 2016 Feb 12;470(3):714-720
pubmed: 26775846
Pediatr Blood Cancer. 2012 Apr;58(4):591-7
pubmed: 21548011
Mol Cell Biol. 2010 Sep;30(17):4149-58
pubmed: 20566697
Nat Genet. 2019 Feb;51(2):296-307
pubmed: 30643249
Blood Adv. 2018 Jun 26;2(12):1449-1458
pubmed: 29941458
Leukemia. 2010 Jul;24(7):1258-64
pubmed: 20445578
Nature. 2010 Dec 2;468(7324):659-63
pubmed: 21124451
FEBS Lett. 2005 Aug 15;579(20):4470-8
pubmed: 16081070
Nat Med. 2018 Jan;24(1):103-112
pubmed: 29227476
Mol Syst Biol. 2013;9:672
pubmed: 23752268
JCI Insight. 2016;1(4):
pubmed: 27123491
J Hematol Oncol. 2020 Oct 20;13(1):140
pubmed: 33081843
J Exp Med. 2019 Jan 7;216(1):231-243
pubmed: 30545902
Pediatr Blood Cancer. 2013 Jan;60(1):31-4
pubmed: 22422485
J Clin Oncol. 2008 Oct 10;26(29):4791-7
pubmed: 18695255
J Biol Chem. 2000 Jun 30;275(26):19594-602
pubmed: 10766745
J Cancer. 2018 Jan 1;9(1):198-204
pubmed: 29290786
Onco Targets Ther. 2014 Feb 18;7:315-24
pubmed: 24570593
Nature. 2010 Dec 2;468(7324):653-8
pubmed: 21124450
Pediatr Hematol Oncol. 2016 Apr;33(3):157-67
pubmed: 27184773
Medicine (Baltimore). 2020 Oct 9;99(41):e22607
pubmed: 33031316
Mol Cell. 2002 Dec;10(6):1403-15
pubmed: 12504015
Sci Rep. 2019 Mar 15;9(1):4634
pubmed: 30874617
Blood. 2015 Oct 8;126(15):1813-22
pubmed: 26219304
Cancer Cell. 2018 May 14;33(5):937-948.e8
pubmed: 29681510
J Clin Oncol. 2017 Feb;35(4):394-401
pubmed: 27870571
Cell Rep. 2020 Dec 22;33(12):108517
pubmed: 33357426
J Exp Med. 2012 Feb 13;209(2):395-406
pubmed: 22291095
J Biol Chem. 2010 Jan 22;285(4):2545-53
pubmed: 19923223
Br J Haematol. 2004 Apr;125(1):31-7
pubmed: 15015965
EMBO J. 2007 Mar 21;26(6):1670-80
pubmed: 17332745
Nature. 2017 Feb 23;542(7642):479-483
pubmed: 28192788
Blood. 2008 Feb 1;111(3):1396-403
pubmed: 17971486
J Exp Med. 2000 Feb 21;191(4):641-50
pubmed: 10684856
Haematologica. 2017 Mar;102(3):541-551
pubmed: 27979924
Mol Cell Biol. 1991 Oct;11(10):5229-43
pubmed: 1922043
Blood. 2014 Feb 13;123(7):950
pubmed: 24526774
Nat Immunol. 2008 Aug;9(8):927-36
pubmed: 18568028
N Engl J Med. 2009 Jan 29;360(5):470-80
pubmed: 19129520
Haematologica. 2014 Feb;99(2):e23-5
pubmed: 24497567
Pediatr Blood Cancer. 2014 Oct;61(10):1779-85
pubmed: 24976218
PLoS One. 2016 Jun 17;11(6):e0157767
pubmed: 27315244
Nucleic Acids Res. 2011 May;39(9):3505-19
pubmed: 21245044
EMBO J. 1998 Oct 1;17(19):5734-43
pubmed: 9755173
Oncotarget. 2016 Jul 19;7(29):46014-46027
pubmed: 27322554
J Biol Chem. 2016 Feb 19;291(8):4004-18
pubmed: 26655717
J Leukoc Biol. 2001 Apr;69(4):675-83
pubmed: 11310856
Mol Cell Biol. 2004 Apr;24(7):2797-807
pubmed: 15024069
Immunity. 2020 Aug 18;53(2):353-370.e8
pubmed: 32735845
Eur J Immunol. 1995 Feb;25(2):399-404
pubmed: 7875201
Blood. 1982 Dec;60(6):1305-9
pubmed: 6982733
J Clin Oncol. 2017 Mar 20;35(9):975-983
pubmed: 28297628
Blood. 2007 Apr 1;109(7):2878-86
pubmed: 17148585
Int J Cancer. 2008 Sep 15;123(6):1240-5
pubmed: 18623087
Nature. 2012 Jan 11;481(7380):157-63
pubmed: 22237106