The Effects of Peripubertal THC Exposure in Neurodevelopmental Rat Models of Psychopathology.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
15 Feb 2023
Historique:
received: 16 12 2022
revised: 29 01 2023
accepted: 06 02 2023
entrez: 25 2 2023
pubmed: 26 2 2023
medline: 3 3 2023
Statut: epublish

Résumé

Adolescent exposure to cannabinoids as a postnatal environmental insult may increase the risk of psychosis in subjects exposed to perinatal insult, as suggested by the two-hit hypothesis of schizophrenia. Here, we hypothesized that peripubertal Δ

Identifiants

pubmed: 36835313
pii: ijms24043907
doi: 10.3390/ijms24043907
pmc: PMC9962163
pii:
doi:

Substances chimiques

Dopamine VTD58H1Z2X
Dronabinol 7J8897W37S
Receptors, Dopamine D3 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Martina Di Bartolomeo (M)

Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.

Tibor Stark (T)

Scientific Core Unit Neuroimaging, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
Department of Pharmacology, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.

Serena Di Martino (S)

Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

Fabio Arturo Iannotti (FA)

Endocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.

Jana Ruda-Kucerova (J)

Department of Pharmacology, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.

Giovanni Luca Romano (GL)

Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

Martin Kuchar (M)

Forensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, 16628 Prague, Czech Republic.
Psychedelic Research Centre, National Institute of Mental Health, Topolová 748, 25067 Klecany, Czech Republic.

Samuele Laudani (S)

Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

Petr Palivec (P)

Forensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, 16628 Prague, Czech Republic.

Fabiana Piscitelli (F)

Endocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.

Carsten T Wotjak (CT)

Central Nervous System Diseases Research (CNSDR), Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach an der Riss, Germany.

Claudio Bucolo (C)

Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

Filippo Drago (F)

Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

Vincenzo Di Marzo (V)

Endocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.
Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health, Faculty of Medicine, Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Quebec City, QC G1V 4G5, Canada.

Claudio D'Addario (C)

Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.

Vincenzo Micale (V)

Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

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Classifications MeSH