Sex Differences in Motor and Non-Motor Symptoms among Spanish Patients with Parkinson's Disease.
Parkinson’s disease
gender
motor
non-motor symptoms
quality of life
sex
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
07 Feb 2023
07 Feb 2023
Historique:
received:
26
12
2022
revised:
31
01
2023
accepted:
01
02
2023
entrez:
25
2
2023
pubmed:
26
2
2023
medline:
26
2
2023
Statut:
epublish
Résumé
Sex plays a role in Parkinson's disease (PD) mechanisms. We analyzed sex difference manifestations among Spanish patients with PD. PD patients who were recruited from the Spanish cohort COPPADIS from January 2016 to November 2017 were included. A cross-sectional and a two-year follow-up analysis were conducted. Univariate analyses and general linear model repeated measure were used. At baseline, data from 681 PD patients (mean age 62.54 ± 8.93) fit the criteria for analysis. Of them, 410 (60.2%) were males and 271 (39.8%) females. There were no differences between the groups in mean age (62.36 ± 8.73 vs. 62.8 ± 9.24; The present study demonstrates that there are important sex differences in PD. Long-term prospective comparative studies are needed.
Sections du résumé
BACKGROUND AND OBJECTIVE
OBJECTIVE
Sex plays a role in Parkinson's disease (PD) mechanisms. We analyzed sex difference manifestations among Spanish patients with PD.
PATIENTS AND METHODS
METHODS
PD patients who were recruited from the Spanish cohort COPPADIS from January 2016 to November 2017 were included. A cross-sectional and a two-year follow-up analysis were conducted. Univariate analyses and general linear model repeated measure were used.
RESULTS
RESULTS
At baseline, data from 681 PD patients (mean age 62.54 ± 8.93) fit the criteria for analysis. Of them, 410 (60.2%) were males and 271 (39.8%) females. There were no differences between the groups in mean age (62.36 ± 8.73 vs. 62.8 ± 9.24;
CONCLUSION
CONCLUSIONS
The present study demonstrates that there are important sex differences in PD. Long-term prospective comparative studies are needed.
Identifiants
pubmed: 36835866
pii: jcm12041329
doi: 10.3390/jcm12041329
pmc: PMC9960095
pii:
doi:
Types de publication
Journal Article
Langues
eng
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