Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations-Review.

clinical manifestation management physiopathology tardive syndrome

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
14 Feb 2023
Historique:
received: 05 12 2022
revised: 06 02 2023
accepted: 10 02 2023
entrez: 25 2 2023
pubmed: 26 2 2023
medline: 26 2 2023
Statut: epublish

Résumé

Tardive syndrome (TS) refers to persistent hyperkinetic, hypokinetic, and sensory complaints appearing after chronic neuroleptics and other dopamine receptor-blocking agents (DRBAs). It is defined as involuntary movements, often rhythmic, choreiform, or athetoid, involving the tongue, face, extremities, and sensory urges such as akathisia and lasts for a few weeks. TS develops in association with neuroleptic medication usage for a few months at least. There is usually a delay between the initiation of the causative drug and the onset of abnormal movements. However, it was soon noted that TS can also develop early, even days or weeks after DRBAs begin. However, the longer the exposure, the greater the risk of developing TS. Tardive dyskinesia, dystonia, akathisia, tremor, and parkinsonism are frequent phenomenologies of this syndrome.

Identifiants

pubmed: 36836033
pii: jcm12041498
doi: 10.3390/jcm12041498
pmc: PMC9967615
pii:
doi:

Types de publication

Editorial

Langues

eng

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Auteurs

Samih Badarny (S)

Neurology Department, Galilee Medical Center, Nahariya 221001, Israel.
Bar Ilan Faculty of Medicine, Zafed 1311502, Israel.

Rima Nassar (R)

Faculty of Medicine, Israel Technion, Haifa 3109601, Israel.

Yazid Badarny (Y)

Neurosurgery Department, Rambam Medical Center, Haifa 3109601, Israel.

Classifications MeSH