Biomechanical Assessment of Red Blood Cells in Pulsatile Blood Flows.

RBC aggregation index blood junction pressure blood velocity blood viscoelasticity microfluidic pulsatile flow microscopic image intensity rheological property

Journal

Micromachines
ISSN: 2072-666X
Titre abrégé: Micromachines (Basel)
Pays: Switzerland
ID NLM: 101640903

Informations de publication

Date de publication:
26 Jan 2023
Historique:
received: 06 01 2023
revised: 24 01 2023
accepted: 24 01 2023
entrez: 25 2 2023
pubmed: 26 2 2023
medline: 26 2 2023
Statut: epublish

Résumé

As rheological properties are substantially influenced by red blood cells (RBCs) and plasma, the separation of their individual contributions in blood is essential. The estimation of multiple rheological factors is a critical issue for effective early detection of diseases. In this study, three rheological properties (i.e., viscoelasticity, RBC aggregation, and blood junction pressure) are measured by analyzing the blood velocity and image intensity in a microfluidic device. Using a single syringe pump, the blood flow rate sets to a pulsatile flow pattern (

Identifiants

pubmed: 36838017
pii: mi14020317
doi: 10.3390/mi14020317
pmc: PMC9958583
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : National Research Foundation of Korea
ID : NRF-2021R1I1A3040338

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Auteurs

Yang Jun Kang (YJ)

Department of Mechanical Engineering, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju 61452, Republic of Korea.

Classifications MeSH