Association between Alcohol Intake and Prostate Cancer Mortality and Survival.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
12 Feb 2023
Historique:
received: 30 12 2022
revised: 03 02 2023
accepted: 07 02 2023
entrez: 25 2 2023
pubmed: 26 2 2023
medline: 3 3 2023
Statut: epublish

Résumé

We conducted a systematic review and meta-analysis to investigate the role of alcohol consumption with the prognosis of prostate cancer (PCa). Published reports were gathered on 15 October 2022, from PUBMED/MEDLINE and EMBASE. We found 19 independent eligible studies on the association between consumption of alcoholic beverages and the risk of fatal PCa (n = 5), PCa mortality (n = 5) in healthy subjects, and PCa patients' survival (n = 7) or surrogates thereof (n = 2). We used random effects meta-analysis to obtain a summary risk estimate (SRE) and 95% confidence intervals (95%CI) for incidence of fatal PCa and PCa mortality. The meta-analysis revealed no association between alcohol consumption and fatal prostate cancer incidence risk in healthy subjects with an indication for publication bias, but omitting the study that mainly increased the between-study heterogeneity, the SRE becomes significant (SRE 1.33, 95%CI 1.12-1.58), and the heterogeneity disappeared (

Identifiants

pubmed: 36839283
pii: nu15040925
doi: 10.3390/nu15040925
pmc: PMC9965886
pii:
doi:

Types de publication

Systematic Review Meta-Analysis Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Governo Italiano
ID : RF-2019-12368771

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Auteurs

Oriana D'Ecclesiis (O)

Department of Experimental Oncology, European Institute of Oncology, IRCCS, 20139 Milan, Italy.

Elisa Pastore (E)

Institute for Cancer Research, Prevention, and Clinical Network (ISPRO), Via Cosimo il Vecchio 2, 50139 Florence, Italy.

Sara Gandini (S)

Department of Experimental Oncology, European Institute of Oncology, IRCCS, 20139 Milan, Italy.

Saverio Caini (S)

Institute for Cancer Research, Prevention, and Clinical Network (ISPRO), Via Cosimo il Vecchio 2, 50139 Florence, Italy.

Giulia Marvaso (G)

Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy.
Division of Radiation Oncology, European Institute of Oncology, IRCCS, 20141 Milan, Italy.

Barbara A Jereczek-Fossa (BA)

Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy.
Division of Radiation Oncology, European Institute of Oncology, IRCCS, 20141 Milan, Italy.

Giulia Corrao (G)

Division of Radiation Oncology, European Institute of Oncology, IRCCS, 20141 Milan, Italy.

Sara Raimondi (S)

Department of Experimental Oncology, European Institute of Oncology, IRCCS, 20139 Milan, Italy.

Federica Bellerba (F)

Department of Experimental Oncology, European Institute of Oncology, IRCCS, 20139 Milan, Italy.

Silvia Ciceri (S)

Division of Epidemiology and Biostatistics, European Institute of Oncology, IRCCS, 20141 Milan, Italy.

Marialetizia Latella (M)

Division of Epidemiology and Biostatistics, European Institute of Oncology, IRCCS, 20141 Milan, Italy.

Nora de Bonfioli Cavalcabò (NB)

Institute for Cancer Research, Prevention, and Clinical Network (ISPRO), Via Cosimo il Vecchio 2, 50139 Florence, Italy.

Benedetta Bendinelli (B)

Institute for Cancer Research, Prevention, and Clinical Network (ISPRO), Via Cosimo il Vecchio 2, 50139 Florence, Italy.

Calogero Saieva (C)

Institute for Cancer Research, Prevention, and Clinical Network (ISPRO), Via Cosimo il Vecchio 2, 50139 Florence, Italy.

Miriam Fontana (M)

Institute for Cancer Research, Prevention, and Clinical Network (ISPRO), Via Cosimo il Vecchio 2, 50139 Florence, Italy.

Patrizia Gnagnarella (P)

Division of Epidemiology and Biostatistics, European Institute of Oncology, IRCCS, 20141 Milan, Italy.

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Classifications MeSH