Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems.
biological macromolecules
biomedical applications
drug delivery systems
ionic liquids
water solubility
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
20 Feb 2023
20 Feb 2023
Historique:
received:
27
11
2022
revised:
05
02
2023
accepted:
11
02
2023
entrez:
25
2
2023
pubmed:
26
2
2023
medline:
26
2
2023
Statut:
epublish
Résumé
Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids "Solutions for Your Success" have received a lot of interest from scientists due to a myriad of applications in the pharmaceutical industry for drug delivery systems as well as targeting different diseases. Solubility is a critical physicochemical property that determines the drug's fate at the target site. Many promising drug candidates fail in various phases of drug research due to poor solubility. In this context, ionic liquids are regarded as effective drug delivery systems for poorly soluble medicines. ILs are also able to combine different anions/cations with other cations/anions to produce salts that satisfy the concept behind the ILs. The important characteristics of ionic liquids are the modularity of their physicochemical properties depending on the application. The review highlights the recent advancement and further applications of ionic liquids to deliver drugs in the pharmaceutical and biomedical fields.
Identifiants
pubmed: 36840024
pii: pharmaceutics15020702
doi: 10.3390/pharmaceutics15020702
pmc: PMC9963759
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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