Ileal Pouch-Anal Anastomosis in the Older Adult: a Review of Postoperative Outcomes and Pouchitis Treatment.

IPAA Older adults Proctocolectomy Ulcerative colitis

Journal

Current treatment options in gastroenterology
ISSN: 1092-8472
Titre abrégé: Curr Treat Options Gastroenterol
Pays: United States
ID NLM: 9815941

Informations de publication

Date de publication:
Dec 2022
Historique:
entrez: 27 2 2023
pubmed: 28 2 2023
medline: 28 2 2023
Statut: ppublish

Résumé

Ileal pouch-anal anastomosis (IPAA) has become the preferred surgical treatment for patients with medically refractive ulcerative colitis (UC). Previous studies have suggested that outcomes of this procedure may be worse in older patients; however, more recent reports have suggested that IPAA in select patients is safe, feasible, and results in good quality of life. In this review, we discuss the recent literature surrounding clinical considerations and treatment management of IPAA in older adults. IPAA complication rates and adverse events are similar in the older adult population, as compared to the younger adult patient population. Although fecal urgency and incontinence may be more common among older adults, chronological age alone is not a contraindication for IPAA surgery, as good quality of life can still be achieved. In this review, we will also discuss the development of pouchitis after IPAA, particularly among older adults, as the emergence of newer biologic drugs has shifted the treatment landscape. IPAA can be a safe and effective treatment modality for older adults with UC, with high self-reported patient satisfaction. Patient optimization and careful case selection are vital to achieving these outcomes, and specialized preoperative assessments and counseling can help facilitate the proper treatment.

Identifiants

pubmed: 36844648
doi: 10.1007/s11938-022-00405-x
pmc: PMC9957085
mid: NIHMS1869036
doi:

Types de publication

Journal Article

Langues

eng

Pagination

564-581

Subventions

Organisme : NIA NIH HHS
ID : R03 AG078927
Pays : United States

Déclaration de conflit d'intérêts

Conflict of Interest Sabrina L. Chen declares that she has no conflict of interest. Adam S. Faye declares that he has no conflict of interest. Shannon Chang declares that she has no conflict of interest.

Références

Eur J Gastroenterol Hepatol. 2012 Jul;24(7):756-8
pubmed: 22395225
Inflamm Bowel Dis. 2001 Nov;7(4):301-5
pubmed: 11720319
Gastroenterology. 2003 May;124(5):1202-9
pubmed: 12730861
Lancet Gastroenterol Hepatol. 2022 Feb;7(2):118-127
pubmed: 34798038
Aliment Pharmacol Ther. 2019 May;49(9):1188-1194
pubmed: 30891808
Curr Treat Options Gastroenterol. 2018 Sep;16(3):275-288
pubmed: 29998454
Inflamm Bowel Dis. 2019 Aug 20;25(9):1569-1576
pubmed: 30810748
J Surg Res. 2018 Sep;229:324-331
pubmed: 29937009
Ann Surg. 2000 Jun;231(6):919-26
pubmed: 10816636
Lancet Gastroenterol Hepatol. 2022 Jan;7(1):69-95
pubmed: 34774224
Clin Gastroenterol Hepatol. 2019 Aug;17(9):1736-1743.e4
pubmed: 30616024
Updates Surg. 2020 Sep;72(3):827-833
pubmed: 31953786
Lancet Gastroenterol Hepatol. 2021 Oct;6(10):826-849
pubmed: 34416186
Aliment Pharmacol Ther. 2020 Oct;52(8):1353-1365
pubmed: 32876349
Surgery. 2009 Oct;146(4):723-9; discussion 729-30
pubmed: 19789032
Scand J Gastroenterol. 2017 Oct;52(10):1078-1085
pubmed: 28599590
Colorectal Dis. 2017 Aug;19(8):756-763
pubmed: 28181378
Aliment Pharmacol Ther. 2010 Jan 15;31(2):228-32
pubmed: 19817724
Aliment Pharmacol Ther. 2017 Mar;45(5):581-592
pubmed: 28008631
J Gastrointest Surg. 2017 Aug;21(8):1304-1308
pubmed: 28470559
Gastroenterol Hepatol (N Y). 2017 Aug;13(8):466-475
pubmed: 28867978
Inflamm Bowel Dis. 2017 May;23(5):781-790
pubmed: 28301429
Int J Colorectal Dis. 2016 Mar;31(3):481-92
pubmed: 26754072
Dis Colon Rectum. 2005 Jun;48(6):1254-62
pubmed: 15868228
United European Gastroenterol J. 2019 Nov;7(9):1215-1225
pubmed: 31700634
Am J Gastroenterol. 2011 Nov;106(11):1889-97
pubmed: 21862997
Clin Gastroenterol Hepatol. 2016 Sep;14(9):1274-81
pubmed: 26656299
Ann Surg. 2003 Sep;238(3):433-41; discussion 442-5
pubmed: 14501509
Br Med J. 1978 Jul 8;2(6130):85-8
pubmed: 667572
Dis Colon Rectum. 2004 Jun;47(6):876-84
pubmed: 15108026
N Engl J Med. 2022 Jan 27;386(4):316-326
pubmed: 35081280
Dig Dis Sci. 2021 May;66(5):1631-1638
pubmed: 32445049
Inflamm Bowel Dis. 2009 Feb;15(2):182-9
pubmed: 18668678
Rev Esp Enferm Dig. 2020 Jan;112(1):59-63
pubmed: 31823641
N Engl J Med. 2017 May 4;376(18):1723-1736
pubmed: 28467869
Inflamm Bowel Dis. 2017 Jun;23(6):882-893
pubmed: 28375885
Scand J Gastroenterol. 2019 Feb;54(2):188-193
pubmed: 30739519
Aliment Pharmacol Ther. 2009 Mar 1;29(5):519-26
pubmed: 19183338
Inflamm Bowel Dis. 2012 Dec;18(12):2232-9
pubmed: 22407820
Dig Dis Sci. 2019 Dec;64(12):3596-3601
pubmed: 31187322
Am J Health Syst Pharm. 2015 Aug 1;72(15):1271-8
pubmed: 26195652
Gastroenterology. 2022 May;162(6):1762-1764
pubmed: 34864071
United European Gastroenterol J. 2020 Nov;8(9):1076-1085
pubmed: 32807038
Colorectal Dis. 2019 Jan;21(1):73-78
pubmed: 30218632
Dig Dis. 2019;37(1):1-10
pubmed: 30293078
Cochrane Database Syst Rev. 2015 Nov 23;(11):CD001176
pubmed: 26593456
Aliment Pharmacol Ther. 2022 Jul;56(1):95-109
pubmed: 35876062
Gastroenterology. 2021 Jan;160(1):445-451
pubmed: 33011177
Curr Gastroenterol Rep. 2003 Oct;5(5):406-13
pubmed: 12959722
J Crohns Colitis. 2013 Nov;7(10):e457-60
pubmed: 23523672
Aliment Pharmacol Ther. 2008 May;27(9):759-64
pubmed: 18298639
Aliment Pharmacol Ther. 2018 Mar;47(5):605-614
pubmed: 29369387
Dis Colon Rectum. 2014 Jan;57(1):5-22
pubmed: 24316941
Dis Colon Rectum. 2007 Apr;50(4):498-508
pubmed: 17279300
Surg Today. 2016 Aug;46(8):939-49
pubmed: 26510664
Inflamm Bowel Dis. 2006 Jan;12(1):29-32
pubmed: 16374255
Digestion. 2020;101(6):737-742
pubmed: 31487725
Digestion. 2020;101 Suppl 1:105-119
pubmed: 31935714
J Crohns Colitis. 2016 Dec;10(12):1437-1444
pubmed: 27252400
Inflamm Bowel Dis. 2019 Mar 14;25(4):767-774
pubmed: 30295784
Int J Colorectal Dis. 2021 Sep;36(9):1937-1943
pubmed: 34160664
Aliment Pharmacol Ther. 2002 Jan;16(1):27-34
pubmed: 11856075
Inflamm Bowel Dis. 2010 Feb;16(2):243-9
pubmed: 19637335
Dig Dis Sci. 1994 Jun;39(6):1193-6
pubmed: 8200250
Aliment Pharmacol Ther. 2002 May;16(5):909-17
pubmed: 11966499
J Crohns Colitis. 2015 Jun;9(6):507-15
pubmed: 25870198
Prim Care. 2017 Dec;44(4):673-692
pubmed: 29132528
Aliment Pharmacol Ther. 2007 May 15;25(10):1231-6
pubmed: 17451569
Aliment Pharmacol Ther. 2018 Mar;47(5):581-587
pubmed: 29266360
Inflamm Bowel Dis. 2012 May;18(5):812-7
pubmed: 21826765
Gut. 2019 Dec;68(Suppl 3):s1-s106
pubmed: 31562236
Inflamm Bowel Dis. 2018 Jan 18;24(2):261-268
pubmed: 29361101
Colorectal Dis. 2011 Feb;13(2):184-90
pubmed: 19906054
J Crohns Colitis. 2017 Sep 1;11(9):1156
pubmed: 28199485
Colorectal Dis. 2021 Aug;23(8):2062-2074
pubmed: 33825296
Gastroenterology. 2019 Apr;156(5):1345-1353.e4
pubmed: 30639677
Dig Dis Sci. 2019 Jul;64(7):1945-1951
pubmed: 30734234
N Engl J Med. 2019 Sep 26;381(13):1201-1214
pubmed: 31553833
Colorectal Dis. 2018 Jan;20(1):44-52
pubmed: 28667683
Dig Liver Dis. 2017 Jan;49(1):17-23
pubmed: 27717794
Clin J Gastroenterol. 2020 Aug;13(4):560-563
pubmed: 32130659
Colorectal Dis. 2011 Feb;13(2):177-83
pubmed: 19878516
Inflamm Bowel Dis. 2017 Dec;23(12):2147-2153
pubmed: 29135694
Gastroenterol Rep (Oxf). 2014 May;2(2):85-91
pubmed: 24759347
Dig Dis Sci. 2022 Jun;67(6):1948-1955
pubmed: 34097166
JGH Open. 2018 Jan 04;2(1):8-14
pubmed: 30483556
J Crohns Colitis. 2016 Apr;10(4):410-7
pubmed: 26721938
J Crohns Colitis. 2014 Jul;8(7):649-53
pubmed: 24394806
Colorectal Dis. 2021 Sep;23(9):2416-2424
pubmed: 34157179
Dis Colon Rectum. 2011 Jan;54(1):15-20
pubmed: 21160308
ANZ J Surg. 2022 Sep;92(9):2180-2184
pubmed: 35434821
Inflamm Bowel Dis. 2022 May 4;28(5):734-744
pubmed: 34245261
Dis Colon Rectum. 2020 May;63(5):639-645
pubmed: 32032200
Gut. 2004 Jan;53(1):108-14
pubmed: 14684584
Surg Endosc. 2017 Mar;31(3):1083-1092
pubmed: 27412123
Gastroenterology. 2000 Aug;119(2):305-9
pubmed: 10930365
Colorectal Dis. 2010 Oct;12(10):1026-32
pubmed: 19624520
Intest Res. 2021 Jan;19(1):1-11
pubmed: 33138344
Curr Treat Options Gastroenterol. 2016 Sep;14(3):285-304
pubmed: 27387455
Clin Gastroenterol Hepatol. 2011 Jan;9(1):30-5
pubmed: 20951835
J Crohns Colitis. 2017 Jun 01;11(6):671-679
pubmed: 27927720
Am J Gastroenterol. 2021 Jan 1;116(1):162-170
pubmed: 32740081

Auteurs

Sabrina L Chen (SL)

Department of Gastroenterology, New York University Grossman School of Medicine, 305 East 33rd Street, NY 10016 New York, USA.

Adam S Faye (AS)

Department of Gastroenterology, New York University Grossman School of Medicine, 305 East 33rd Street, NY 10016 New York, USA.

Shannon Chang (S)

Department of Gastroenterology, New York University Grossman School of Medicine, 305 East 33rd Street, NY 10016 New York, USA.

Classifications MeSH