Methotrexate-Induced Apoptotic Colopathy in Crohn's Disease.
Crohn's disease
methotrexate
pathology
Journal
ACG case reports journal
ISSN: 2326-3253
Titre abrégé: ACG Case Rep J
Pays: United States
ID NLM: 101638398
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
received:
13
10
2022
accepted:
09
01
2023
entrez:
27
2
2023
pubmed:
28
2
2023
medline:
28
2
2023
Statut:
epublish
Résumé
Apoptotic colopathy is a pattern of injury not frequently associated with Crohn's disease (CD) despite its association with medications used in CD management. We describe a patient with CD on methotrexate who underwent a diagnostic colonoscopy for abdominal pain and diarrhea, with biopsies demonstrating apoptotic colopathy. After methotrexate discontinuation, repeat colonoscopy demonstrated resolution of apoptotic colopathy in addition to diarrhea improvement.
Identifiants
pubmed: 36846357
doi: 10.14309/crj.0000000000000980
pii: ACGCR-22-0680
pmc: PMC9949825
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e00980Informations de copyright
© 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.
Références
J Clin Pathol. 2018 Dec;71(12):1033-1040
pubmed: 30275102