Scatter correction of 4D cone beam computed tomography to detect dosimetric effects due to anatomical changes in proton therapy for lung cancer.
4D
CBCT
adaptive radiotherapy
cone beam CT
lung cancer
proton therapy
scatter correction
virtual CT
Journal
Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746
Informations de publication
Date de publication:
Aug 2023
Aug 2023
Historique:
revised:
01
02
2023
received:
24
06
2022
accepted:
14
02
2023
medline:
15
8
2023
pubmed:
28
2
2023
entrez:
27
2
2023
Statut:
ppublish
Résumé
The treatment of moving tumor entities is expected to have superior clinical outcomes, using image-guided adaptive intensity-modulated proton therapy (IMPT). For 21 lung cancer patients, IMPT dose calculations were performed on scatter-corrected 4D cone beam CTs (4DCBCT A 4DCBCT correction workflow, previously validated on a phantom, generates 4DvCT (CT-to-CBCT deformable registration) and 4DCBCT Quality enhancements of 4DvCT and 4DCBCT This retrospective study shows the feasibility of daily proton dose calculation on 4DCBCT
Sections du résumé
BACKGROUND
BACKGROUND
The treatment of moving tumor entities is expected to have superior clinical outcomes, using image-guided adaptive intensity-modulated proton therapy (IMPT).
PURPOSE
OBJECTIVE
For 21 lung cancer patients, IMPT dose calculations were performed on scatter-corrected 4D cone beam CTs (4DCBCT
METHODS
METHODS
A 4DCBCT correction workflow, previously validated on a phantom, generates 4DvCT (CT-to-CBCT deformable registration) and 4DCBCT
RESULTS
RESULTS
Quality enhancements of 4DvCT and 4DCBCT
CONCLUSIONS
CONCLUSIONS
This retrospective study shows the feasibility of daily proton dose calculation on 4DCBCT
Substances chimiques
Protons
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4981-4992Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : 399148265
Organisme : Research Training Group GRK
ID : 2274
Informations de copyright
© 2023 The Authors. Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine.
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