Enterobacterales carbapenemases cefepime taniborbactam zidebactam β-lactam enhancer β-lactamase inhibitor

Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
27 Feb 2023
Historique:
entrez: 27 2 2023
pubmed: 28 2 2023
medline: 28 2 2023
Statut: aheadofprint

Résumé

In recent times, discovery efforts for novel antibiotics have mostly targeted carbapenemase-producing Gram-negative organisms. Two different combination approaches are pertinent: β-lactam-β-lactamase inhibitor (BL/BLI) or β-lactam-β-lactam enhancer (BL/BLE). Cefepime combined with a BLI, taniborbactam, or with a BLE, zidebactam, has been shown to be promising. In this study, we determined the

Identifiants

pubmed: 36847537
doi: 10.1128/spectrum.04925-22
pmc: PMC10100882
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0492522

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Auteurs

Yamuna Devi Bakthavatchalam (YD)

Department of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.

Divyaa Elangovan (D)

Department of Microbiology, Panimalar Medical College Hospital and Research Institute, Chennai, India.

Subha Vajjiravelu Jaganathan (SV)

Department of Microbiology, Meenakshi Medical College and Research Institute, Kanchipuram, India.

Nivedhana Subburaju (N)

Department of Microbiology, Rainbow Children's Hospital and Perinatal Care, Hyderabad, India.

Abirami Shankar (A)

Department of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.

Yuvasri Manokaran (Y)

Department of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.

Sudarsana J (S)

Department of Microbiology, Baby Memorial Hospital, Kozhikode, India.

Rema Devi (R)

Department of Microbiology, Dr. Somervell Memorial CSI Medical College and Hospital, Thiruvananthapuram, India.

Sujata Baveja (S)

Department of Microbiology, Lokmanya Tilak Municipal General Hospital and Medical College (Sion Hospital), Mumbai, India.

Sheela Devi (S)

Department of Microbiology, Pondicherry Institute of Medical Sciences, Kalapet, India.

Jayakumar S (J)

Department of Microbiology, Saveetha Medical College and Hospital, Chennai, India.

Sanjay Bhattacharya (S)

Department of Microbiology, Tata Medical Center, Kolkata, India.

Rudresh S M (R)

Department of Microbiology, ESI Post Graduate Institute of Medical Science and Research, Bengaluru, India.

Bineshlal Yesudhason (B)

Department of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.

Vignesh Shetty (V)

Department of Medicine, Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge, Cambridge, United Kingdom.

Ankur Mutreja (A)

Department of Medicine, Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge, Cambridge, United Kingdom.

Abi Manesh (A)

Department of Infectious Disease, Christian Medical College and Hospital, Vellore, India.

George M Varghese (GM)

Department of Infectious Disease, Christian Medical College and Hospital, Vellore, India.

Charis A Marwick (CA)

Population Health and Genomics, University of Dundee, Dundee, United Kingdom.

Benjamin J Parcell (BJ)

Ninewells Hospital and Medical School, Dundee, United Kingdom.

Ian H Gilbert (IH)

Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom.

Balaji Veeraraghavan (B)

Department of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India.

Classifications MeSH