Bioinspired Membrane Interfaces: Controlling Actomyosin Architecture and Contractility.


Journal

ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991

Informations de publication

Date de publication:
08 Mar 2023
Historique:
pubmed: 28 2 2023
medline: 11 3 2023
entrez: 27 2 2023
Statut: ppublish

Résumé

The creation of biologically inspired artificial lipid bilayers on planar supports provides a unique platform to study membrane-confined processes in a well-controlled setting. At the plasma membrane of mammalian cells, the linkage of the filamentous (F)-actin network is of pivotal importance leading to cell-specific and dynamic F-actin architectures, which are essential for the cell's shape, mechanical resilience, and biological function. These networks are established through the coordinated action of diverse actin-binding proteins and the presence of the plasma membrane. Here, we established phosphatidylinositol-4,5-bisphosphate (PtdIns[4,5]P

Identifiants

pubmed: 36848241
doi: 10.1021/acsami.3c00061
pmc: PMC9999349
doi:

Substances chimiques

Actomyosin 9013-26-7
Actins 0
Lipid Bilayers 0
Phosphatidylinositols 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

11586-11598

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Auteurs

Nils L Liebe (NL)

Institut für Organische und Biomolekulare Chemie, Georg-August Universität, Tammannstr. 2, Göttingen 37077, Germany.

Ingo Mey (I)

Institut für Organische und Biomolekulare Chemie, Georg-August Universität, Tammannstr. 2, Göttingen 37077, Germany.

Loan Vuong (L)

Institut für Organische und Biomolekulare Chemie, Georg-August Universität, Tammannstr. 2, Göttingen 37077, Germany.

Fadi Shikho (F)

Institut für Organische und Biomolekulare Chemie, Georg-August Universität, Tammannstr. 2, Göttingen 37077, Germany.

Burkhard Geil (B)

Institut für Physikalische Chemie, Georg-August Universität, Tammannstr. 6, Göttingen 37077, Germany.

Andreas Janshoff (A)

Institut für Physikalische Chemie, Georg-August Universität, Tammannstr. 6, Göttingen 37077, Germany.

Claudia Steinem (C)

Institut für Organische und Biomolekulare Chemie, Georg-August Universität, Tammannstr. 2, Göttingen 37077, Germany.
Max-Planck-Institut für Dynamik und Selbstorganisation, Am Fassberg 17, Göttingen 37077, Germany.

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Classifications MeSH