A case of COVID-19-associated fulminant myocarditis due to SARS-CoV-2 omicron BA.2 sub-lineage in an unvaccinated female.
COVID-19
Endomyocardial biopsy
Fulminant myocarditis
Mechanical circulation support
The omicron variant
Journal
Journal of cardiology cases
ISSN: 1878-5409
Titre abrégé: J Cardiol Cases
Pays: Japan
ID NLM: 101549579
Informations de publication
Date de publication:
23 Feb 2023
23 Feb 2023
Historique:
received:
12
10
2022
revised:
16
02
2023
accepted:
17
02
2023
entrez:
28
2
2023
pubmed:
1
3
2023
medline:
1
3
2023
Statut:
aheadofprint
Résumé
COVID-19-associated myocarditis can be a lethal complication in previous variants, but it is not well understood in the Omicron variant. We present an unvaccinated case of COVID-19-associated fulminant myocarditis due to the Omicron BA.2 sub-lineage requiring mechanical circulatory support (MCS). A 66-year-old female without vaccination against SARS-CoV-2 was hospitalized due to COVID-19. On the next day, she was transferred to our hospital due to the development of fulminant myocarditis. After arrival, she was treated with Impella CP and venoarterial extracorporeal membrane oxygenation due to unstable hemodynamics. In addition to MCS, we treated her with inotropes, methylprednisolone, tocilizumab, and remdesivir. Left ventricular contraction gradually improved, and MCS was removed on day 8. Endomyocardial biopsy showed mild interstitial infiltration of CD3 Although the Omicron variant is thought to be generally less severe, COVID-19-associated fulminant myocarditis, as in this case, can occur. The vaccination against the Omicron variant should be considered to prevent from developing severe illness.
Identifiants
pubmed: 36852014
doi: 10.1016/j.jccase.2023.02.016
pii: S1878-5409(23)00029-4
pmc: PMC9946881
doi:
Types de publication
Case Reports
Langues
eng
Informations de copyright
© 2023 Japanese College of Cardiology. Published by Elsevier Ltd. .
Déclaration de conflit d'intérêts
The authors declare that there is no conflict of interest.
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