New standards for the management of nose vestibule malignancies.
Nasal vestibule carcinoma
TNM classification
brachytherapy
interventional radiotherapy
squamous cell carcinoma
total rhinectomy
Journal
Acta oto-laryngologica
ISSN: 1651-2251
Titre abrégé: Acta Otolaryngol
Pays: England
ID NLM: 0370354
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
medline:
28
3
2023
pubmed:
2
3
2023
entrez:
1
3
2023
Statut:
ppublish
Résumé
Nasal vestibule squamous cell carcinoma (NVSCC) is an ill-defined underestimated condition. To define the current standard of care. We review recent acquisitions concerning clinical features and therapeutic approaches. The current AJCC staging system, which attributes to nasal vestibule the same topographic code as nasal cavity proper and the same T-classification criteria as ethmoid, appears inadequate.As for treatment of primary lesions without bone invasion, current evidence suggests that brachytherapy is at least equivalent to surgery and superior to external beams in terms of oncological outcomes, and superior to both modalities in terms of cosmesis and function. As for classification and staging, the nasal vestibule should be defined as a subsite of the nose and paranasal sinuses, distinct from the 'nasal cavity proper and ethmoid', with specific topographic code and T-classification criteria. This will improve the assessment of prognosis and prevalence, underestimated also because of misdiagnosis with skin cancers.Secondly, brachytherapy should become the new standard for the treatment of primary lesions without bone invasion. To optimize the advantages of brachytherapy, we propose novel anatomic criteria for the implantation. Increasing evidence supports a paradigm shift in staging and treatment of NVSCC.
Sections du résumé
BACKGROUND
UNASSIGNED
Nasal vestibule squamous cell carcinoma (NVSCC) is an ill-defined underestimated condition.
AIM/OBJECTIVE
UNASSIGNED
To define the current standard of care.
MATERIAL AND METHODS
UNASSIGNED
We review recent acquisitions concerning clinical features and therapeutic approaches.
RESULTS
UNASSIGNED
The current AJCC staging system, which attributes to nasal vestibule the same topographic code as nasal cavity proper and the same T-classification criteria as ethmoid, appears inadequate.As for treatment of primary lesions without bone invasion, current evidence suggests that brachytherapy is at least equivalent to surgery and superior to external beams in terms of oncological outcomes, and superior to both modalities in terms of cosmesis and function.
CONCLUSIONS
UNASSIGNED
As for classification and staging, the nasal vestibule should be defined as a subsite of the nose and paranasal sinuses, distinct from the 'nasal cavity proper and ethmoid', with specific topographic code and T-classification criteria. This will improve the assessment of prognosis and prevalence, underestimated also because of misdiagnosis with skin cancers.Secondly, brachytherapy should become the new standard for the treatment of primary lesions without bone invasion. To optimize the advantages of brachytherapy, we propose novel anatomic criteria for the implantation.
SIGNIFICANCE
UNASSIGNED
Increasing evidence supports a paradigm shift in staging and treatment of NVSCC.
Identifiants
pubmed: 36855802
doi: 10.1080/00016489.2023.2179662
doi:
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM