Multi-criterion optimization of invasive antenna applicators for Au@Fe

Magnetic nanoparticle (MNP) mediated microwave ablation has the great potential at present to address challenges associated with treatment planning such as maximum heat generation in the vicinity of targeted tissues in lesser penetration time. Further, the antenna applicators injected in human phantom must be rigid and thin. The derivative-free optimization algorithms are carried out for optimum design of monopole, slot, dipole, and tapered slot antenna applicators for ablation of tumour tissues invasively. It is found that in terms of input impedance matching, the used multi-criterion Nelder-Mead optimization performs efficiently for tapered slot applicator achieving