Neuroendocrine Tumor Therapy Response Assessment.

Humans Neuroendocrine Tumors Somatostatin
DOTA-Tyr(3)-octreotate NETest Neuroendocrine neoplasms PPQ Peptide receptor radionucleotide therapies Response

Journal

PET clinics
ISSN: 1879-9809
Titre abrégé: PET Clin
Pays: United States
ID NLM: 101260152

Informations de publication

Date de publication:
Apr 2023
Historique:
entrez: 1 3 2023
pubmed: 2 3 2023
medline: 4 3 2023
Statut: ppublish

Résumé

Peptide receptor radionuclide therapy has become an integral part of management of neuroendocrine neoplasms. Gallium-68- and lutetium-177-labeled somatostatin receptor analogues have replaced yttrium-90- and 111-indium-based tracers. Several newer targeted therapies are also being used in clinical and research settings. It is imperative to accurately evaluate the response to these agents. The characteristics of NENs and the response patterns of the targeted therapies make response assessment in this group challenging. This article provides an overview of the strengths and weaknesses of the various biomarkers available for response assessment.

Identifiants

DOI: 10.1016/j.cpet.2022.11.009 PMID: 36858748
pubmed: 36858748
pii: S1556-8598(22)00096-7
doi: 10.1016/j.cpet.2022.11.009
pii:
doi:

Substances chimiques

Somatostatin 51110-01-1

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

267-286

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Vetri Sudar Jayaprakasam (VS)

Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Lisa Bodei (L)

Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: bodeil@mskcc.org.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Neuroendocrine Tumor Therapy Response Assessment.
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroendocrines › Neuroendocrine Tumor Therapy Response Assessment.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Neuropeptides › Hormones hypothalamiques › Hormones hypothalamiques hypophysotropes inhibitrices › Somatostatine › Neuroendocrine Tumor Therapy Response Assessment.