Group B streptococcus virulence factors associated with different clinical syndromes: Asymptomatic carriage in pregnant women and early-onset disease in the newborn.
Orthodox Jews
Streptococcus agalactiae
antibiotic resistance
early-onset sepsis
group B streptococcus
intra uterine fetal death
serotype
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2023
2023
Historique:
received:
08
11
2022
accepted:
23
01
2023
entrez:
2
3
2023
pubmed:
3
3
2023
medline:
3
3
2023
Statut:
epublish
Résumé
Group B streptococcus (GBS) harbors many virulence factors but there is limited data regarding their importance in colonization in pregnancy and early-onset disease (EOD) in the newborn. We hypothesized that colonization and EOD are associated with different distribution and expression of virulence factors. We studied 36 GBS EOD and 234 GBS isolates collected during routine screening. Virulence genes (pilus-like structures- Serotype III (ST17) was significantly associated with EOD and serotype VI (ST1) with colonization. There was a significant difference in the distribution of
Sections du résumé
Background
UNASSIGNED
Group B streptococcus (GBS) harbors many virulence factors but there is limited data regarding their importance in colonization in pregnancy and early-onset disease (EOD) in the newborn. We hypothesized that colonization and EOD are associated with different distribution and expression of virulence factors.
Methods
UNASSIGNED
We studied 36 GBS EOD and 234 GBS isolates collected during routine screening. Virulence genes (pilus-like structures-
Results
UNASSIGNED
Serotype III (ST17) was significantly associated with EOD and serotype VI (ST1) with colonization.
Conclusion
UNASSIGNED
There was a significant difference in the distribution of
Identifiants
pubmed: 36860481
doi: 10.3389/fmicb.2023.1093288
pmc: PMC9968972
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1093288Informations de copyright
Copyright © 2023 Schindler, Rahav, Nissan, Treygerman, Prajgrod, Attia, Raz, Valenci, Tekes-Manova and Maor.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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