Macrophage inflammatory protein-1β as a novel therapeutic target for renal protection in diabetic kidney disease.

Animals Mice Diabetes Mellitus / pathology Diabetic Nephropathies / pathology Fibrosis Inflammation / pathology Kidney / physiology Mice, Knockout Podocytes
Chemokine Diabetic kidney disease Inflammation Macrophage inflammatory protein-1β Podocyte

Journal

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
ISSN: 1950-6007
Titre abrégé: Biomed Pharmacother
Pays: France
ID NLM: 8213295

Informations de publication

Date de publication:
May 2023
Historique:
received: 05 01 2023
revised: 15 02 2023
accepted: 23 02 2023
medline: 3 4 2023
pubmed: 3 3 2023
entrez: 2 3 2023
Statut: ppublish

Résumé

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease worldwide and the prevalence of DKD has increased over recent decades. Inflammation is involved in the development and progression of DKD. In this study, we explored the potential role of macrophage inflammatory protein-1β (MIP-1β) in DKD. Clinical non-diabetic subjects and DKD patients with different levels of urine albumin-to-creatinine ratio (ACR) were enrolled in the study. Lepr

Identifiants

DOI: 10.1016/j.biopha.2023.114450 PMID: 36863097
pubmed: 36863097
pii: S0753-3322(23)00238-X
doi: 10.1016/j.biopha.2023.114450
pii:
doi:

Substances chimiques

Ccl4 protein, mouse 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

114450

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest statement The authors declare that there are no conflicts of interest.

Auteurs

Ting-Ting Chang (TT)

Department and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei, Taiwan; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address: tf0619@nycu.edu.tw.

Szu-Yuan Li (SY)

School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Liang-Yu Lin (LY)

School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Ching Chen (C)

Department and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei, Taiwan; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Jaw-Wen Chen (JW)

Department and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei, Taiwan; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Healthcare and Services Center, Taipei Veterans General Hospital, Taipei, Taiwan; Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Cardiovascular Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address: jwchen@vghtpe.gov.tw.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Macrophage inflammatory protein-1β as a novel...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Macrophage inflammatory protein-1β as a novel...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Macrophage inflammatory protein-1β as a novel...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Complications du diabète › Néphropathies diabétiques › Macrophage inflammatory protein-1β as a novel...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Macrophage inflammatory protein-1β as a novel...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Macrophage inflammatory protein-1β as a novel...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Macrophage inflammatory protein-1β as a novel...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Macrophage inflammatory protein-1β as a novel...
questionsmedicales.fr › Cellules › Cellules épithéliales › Podocytes › Macrophage inflammatory protein-1β as a novel...