Preventive and therapeutic effects of an exopolysaccharide produced by Lacticaseibacillus rhamnosus on alcoholic gastric ulcers.
Alcoholic gastric ulcer
Gastric flora
Transientreceptorpotentialvanilloid-1
lactic acid bacteria
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
30 Apr 2023
30 Apr 2023
Historique:
received:
01
09
2022
revised:
26
01
2023
accepted:
22
02
2023
medline:
10
4
2023
pubmed:
3
3
2023
entrez:
2
3
2023
Statut:
ppublish
Résumé
Crude exopolysaccharides produced by Lacticaseibacillus rhamnosus SHA113 were previously found to exhibit anti-alcoholic gastric ulcer activity in mice, but their major active fraction, structural characteristics, and underlying mechanisms remain unknown. Here, LRSE1 was identified as the active exopolysaccharide fraction produced by L. rhamnosus SHA113 responsible for the above effects. Purified LRSE1 had a molecular weight of 4.9 × 10
Identifiants
pubmed: 36863673
pii: S0141-8130(23)00739-0
doi: 10.1016/j.ijbiomac.2023.123845
pii:
doi:
Substances chimiques
Phosphatidylinositol 3-Kinases
EC 2.7.1.-
Galactose
X2RN3Q8DNE
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
123845Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.