IFN-λ is protective against lethal oral

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
24 Feb 2023
Historique:
pubmed: 4 3 2023
medline: 4 3 2023
entrez: 3 3 2023
Statut: epublish

Résumé

Interferons are essential for innate and adaptive immune responses against a wide variety of pathogens. Interferon lambda (IFN-λ) protects mucosal barriers during pathogen exposure. The intestinal epithelium is the first contact site for

Identifiants

DOI: 10.1101/2023.02.24.529861 PMID: 36865100 PMC: PMC9980175
pubmed: 36865100
doi: 10.1101/2023.02.24.529861
pmc: PMC9980175
pii:
doi:

Types de publication

Preprint

Langues

eng

Déclaration de conflit d'intérêts

Competing interests The authors declare that they have no competing interests.

Auteurs

Mateo Murillo-León (M)

Institute of Virology, Medical Center University of Freiburg, 79104 Freiburg, Germany.
Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.

Aura M Bastidas-Quintero (AM)

Institute of Virology, Medical Center University of Freiburg, 79104 Freiburg, Germany.
Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.

Niklas S Endres (NS)

Institute of Virology, Medical Center University of Freiburg, 79104 Freiburg, Germany.
Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.
Current address:Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Daniel Schnepf (D)

Institute of Virology, Medical Center University of Freiburg, 79104 Freiburg, Germany.
Current address: Immunoregulation Laboratory, The Francis Crick Institute, London, UK.

Estefanía Delgado-Betancourt (E)

FG 16: Mycotic and Parasitic Agents and Mycobacteria, Robert Koch-Institute, Berlin, Germany.

Annette Ohnemus (A)

Institute of Virology, Medical Center University of Freiburg, 79104 Freiburg, Germany.
Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.

Gregory A Taylor (GA)

Departments of Medicine; Molecular Genetics and Microbiology; and Immunology; and Center for the Study of Aging and Human Development, Duke University Medical Center, NC 27710 Durham, North Carolina, United States of America.
Geriatric Research, Education, and Clinical Center, Durham VA Health Care System, NC 27705 Durham, North Carolina, United States of America.

Martin Schwemmle (M)

Institute of Virology, Medical Center University of Freiburg, 79104 Freiburg, Germany.
Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.

Peter Staeheli (P)

Institute of Virology, Medical Center University of Freiburg, 79104 Freiburg, Germany.
Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.

Tobias Steinfeldt (T)

Institute of Virology, Medical Center University of Freiburg, 79104 Freiburg, Germany.
Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.

Classifications MeSH