The Hedgehog/GLI signaling pathway activates transcription of Slug (Snail2) in melanoma cells.
GLI family zinc finger
Hedgehog signaling
Slug
melanoma
melanoma-associated transcription factor
Journal
Oncology reports
ISSN: 1791-2431
Titre abrégé: Oncol Rep
Pays: Greece
ID NLM: 9422756
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
12
10
2022
accepted:
27
01
2023
entrez:
3
3
2023
pubmed:
4
3
2023
medline:
7
3
2023
Statut:
ppublish
Résumé
In melanoma and other cancers, invasion, epithelial-to-mesenchymal transition, metastasis and cancer stem cell maintenance are regulated by transcription factors including the Snail family. Slug (Snail2) protein generally supports migration and apoptosis resistance. However, its role in melanoma is not completely understood. The present study investigated the transcriptional regulation of the
Identifiants
pubmed: 36866769
doi: 10.3892/or.2023.8512
pii: 75
pmc: PMC10018456
doi:
pii:
Substances chimiques
Hedgehog Proteins
0
Transcription Factors
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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