Dermoscopic approach for differential diagnosing of autoimmune bullous disease: pemphigus vulgaris, pemphigus foliaceus, and IgA pemphigus.
Journal
International journal of dermatology
ISSN: 1365-4632
Titre abrégé: Int J Dermatol
Pays: England
ID NLM: 0243704
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
revised:
08
01
2023
received:
11
04
2021
accepted:
07
02
2023
medline:
11
5
2023
pubmed:
4
3
2023
entrez:
3
3
2023
Statut:
ppublish
Résumé
Dermoscopy is a noninvasive technique for the evaluation of different pigments and microstructures of the epidermis, dermoepidermal junction, and papillary dermis that are not apparent to the naked eye, which therefore improves diagnostic accuracy. This study aims to describe the characteristic dermoscopic features of bullous diseases and analyze the characteristic dermoscopic features of bullous diseases of the skin and hair. A descriptive study was conducted to describe and analyze the characteristic dermoscopic features of bullous diseases in the Zagazig University Hospitals. This study enrolled 22 patients. Dermoscopy revealed yellow hemorrhagic crusts in all patients and white yellow structure with red halo in 90.9% of patients. Pemphigus vulgaris patients were identified by the presence of dermoscopic clues such as bluish deep discoloration, tubular scaling, black dots, hair casts, hair tufts, yellow dots with whitish halos (fried egg sign) and yellow follicular pustules that are not seen in pemphigus foliaceus and IgA pemphigus. Dermoscopy is an important tool that serves as a link between clinical and histopathological diagnoses, and it can easily be used in daily practice. Several suggestive dermoscopic features can help in the differential diagnosis of autoimmune bullous disease but only after making a provisional clinical diagnosis. Dermoscopy is a very useful tool in the differentiation of pemphigus subtypes.
Substances chimiques
Immunoglobulin A
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
770-775Informations de copyright
© 2023 the International Society of Dermatology.
Références
Kridin K. Pemphigus group: overview, epidemiology, mortality, and comorbidities. Immunol Res. 2018;66(2):255-70.
Kridin K, Schmidt E. Epidemiology of pemphigus. JID Innov. 2021;1(1):100004.
Schmidt E, Goebeler M, Hertl M, Sárdy M, Sitaru C, Eming R, et al. S2k guideline for the diagnosis of pemphigus vulgaris/foliaceus and bullous pemphigoid. J Dtsch Dermatol Ges. 2015;13(7):713-27.
Pollmann R, Schmidt T, Eming R, Hertl M. Pemphigus: a comprehensive review on pathogenesis, clinical presentation and novel therapeutic approaches. Clin Rev Allergy Immunol. 2018;54(1):1-25.
Errichetti E, Stinco G. Dermoscopy in general dermatology: a practical overview. Dermatol Ther. 2016;6(4):471-507.
Errichetti E, Stinco G. Dermatoscopy in life-threatening and severe acute rashes. Clin Dermatol. 2020;38(1):113-21.
Chan GJ. Dermoscopy: the dermatologists' stethoscope? Hong Kong J Dermatol Venereol. 2013;21(3):111-3.
Sar-Pomian M, Kurzeja M, Rudnicka L, Olszewska M. The value of trichoscopy in the differential diagnosis of scalp lesions in pemphigus vulgaris and pemphigus foliaceus. An Bras Dermatol. 2014;89:1007-12.
Fabris MR, Melo CP, Melo DF. Folliculitis decalvans: the use of dermatoscopy as an auxiliary tool in clinical diagnosis. An Bras Dermatol. 2013;88:814-6.
Doche I, Vincenzi C, Tosti A. Casts and pseudocasts. J Am Acad Dermatol. 2016;75(4):e147-8.
Lacarrubba F, Verzì AE, Micali G. Trichoscopy in the differential diagnosis of pseudonits. Skin Appendage Disord. 2019;5(3):142-5.
Kurzeja M, Rakowska A, Rudnicka L, Olszewska M. Criteria for diagnosing pemphigus vulgaris and pemphigus foliaceus by reflectance confocal microscopy. Skin Res Technol. 2012;18(3):339-46.