Meningitis-retention syndrome: a review and update of an unrecognized clinical condition.


Journal

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 17 12 2022
accepted: 21 02 2023
medline: 15 5 2023
pubmed: 4 3 2023
entrez: 3 3 2023
Statut: ppublish

Résumé

We summarized the clinical and radiological characteristics of meningitis-retention syndrome (MRS), its therapeutic options, and urological outcome, to better understand the pathogenesis of this syndrome and to evaluate the effectiveness of corticosteroids in reducing the period of urinary retention. We reported a new case of MRS in a male adolescent. We also reviewed the previously 28 reported cases of MRS, collected from inception up to September 2022. MRS is characterized by aseptic meningitis and urinary retention. The mean length of the interval between the onset of the neurological signs and the urinary retention was 6.4 days. In most cases, no pathogens were isolated in cerebrospinal fluid, except for 6 cases in which Herpesviruses were detected. The urodynamic study resulted in a detrusor underactivity, with a mean period for urination recovery of 4.5 weeks, regardless of therapies. Neurophysiological studies and electromyographic examination are not pathological, distinguishing MRS from polyneuropathies. Although there are no encephalitic symptoms or signs, and the magnetic resonance is often normal, MRS may represent a mild form of acute disseminated encephalomyelitis, without radiological detectable medullary involvement, due to the prompt use of steroids. It is believed that MRS is a self-limited disease, and no evidence suggests the effectiveness of steroids, antibiotics, and antiviral treatment in its clinical course.

Identifiants

pubmed: 36867276
doi: 10.1007/s10072-023-06704-0
pii: 10.1007/s10072-023-06704-0
pmc: PMC10175389
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1949-1957

Informations de copyright

© 2023. The Author(s).

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Auteurs

Francesco Pellegrino (F)

Department of Pediatric and Public Health Sciences, Regina Margherita Children's Hospital, Postgraduate School of Pediatrics, University of Turin, Piazza Polonia 64, Turin, Italy. f.pellegrino@unito.it.

Elisa Funiciello (E)

Department of Pediatric and Public Health Sciences, Regina Margherita Children's Hospital, Postgraduate School of Pediatrics, University of Turin, Piazza Polonia 64, Turin, Italy.

Giulia Pruccoli (G)

Department of Pediatric and Public Health Sciences, Infectious Diseases Unit, Regina Margherita Children's Hospital, Turin, Italy.

Erika Silvestro (E)

Department of Pediatric and Public Health Sciences, Infectious Diseases Unit, Regina Margherita Children's Hospital, Turin, Italy.

Carlo Scolfaro (C)

Department of Pediatric and Public Health Sciences, Infectious Diseases Unit, Regina Margherita Children's Hospital, Turin, Italy.

Federica Mignone (F)

Department of Pediatric and Public Health Sciences, Infectious Diseases Unit, Regina Margherita Children's Hospital, Turin, Italy.

Aba Tocchet (A)

Child and Adolescent Neurology and Psychiatry Division, Città Della Salute E Della Scienza Hospital, University of Turin, Turin, Italy.

Luca Roasio (L)

Pediatric Department, E. Agnelli Hospital, Via Brigata Cagliari 39, Pinerolo, TO, Italy.

Silvia Garazzino (S)

Department of Pediatric and Public Health Sciences, Infectious Diseases Unit, Regina Margherita Children's Hospital, Turin, Italy.

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