Endothelial and Leptin Receptor


Journal

Developmental cell
ISSN: 1878-1551
Titre abrégé: Dev Cell
Pays: United States
ID NLM: 101120028

Informations de publication

Date de publication:
13 03 2023
Historique:
received: 14 05 2022
revised: 08 12 2022
accepted: 06 02 2023
pmc-release: 13 03 2024
pubmed: 4 3 2023
medline: 17 3 2023
entrez: 3 3 2023
Statut: ppublish

Résumé

Mammalian hematopoietic stem cells (HSCs) colonize the bone marrow during late fetal development, and this becomes the major site of hematopoiesis after birth. However, little is known about the early postnatal bone marrow niche. We performed single-cell RNA sequencing of mouse bone marrow stromal cells at 4 days, 14 days, and 8 weeks after birth. Leptin-receptor-expressing (LepR

Identifiants

pubmed: 36868235
pii: S1534-5807(23)00045-X
doi: 10.1016/j.devcel.2023.02.003
pmc: PMC10035381
mid: NIHMS1875763
pii:
doi:

Substances chimiques

Receptors, Leptin 0
Stem Cell Factor 0
leptin receptor, mouse 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

348-360.e6

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK118745
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NHLBI NIH HHS
ID : F32 HL124947
Pays : United States

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

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Auteurs

Nergis Kara (N)

Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Yuanyuan Xue (Y)

Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Zhiyu Zhao (Z)

Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Malea M Murphy (MM)

Department of Medical Physiology, Texas A&M School of Medicine, Bryan, TX 77807, USA.

Stefano Comazzetto (S)

Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Ashley Lesser (A)

Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Liming Du (L)

Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Sean J Morrison (SJ)

Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: sean.morrison@utsouthwestern.edu.

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Classifications MeSH