Impact of Intensive Care Unit Nutrition on the Microbiome and Patient Outcomes.

Microbiome Nutrition Sepsis Short-chain fatty acids Soluble fiber

Journal

Anesthesiology clinics
ISSN: 1932-2275
Titre abrégé: Anesthesiol Clin
Pays: United States
ID NLM: 101273663

Informations de publication

Date de publication:
Mar 2023
Historique:
entrez: 5 3 2023
pubmed: 6 3 2023
medline: 8 3 2023
Statut: ppublish

Résumé

The bipartite relationship between nutrition and the intestinal microbiome represents an exciting frontier in critical care medicine. In this review, the authors first address these topics independently, leading with a summary of recent clinical studies assessing intensive care unit nutritional strategies, followed by an exploration of the microbiome in the context of perioperative and intensive care, including recent clinical data implicating microbial dysbiosis as a key driver of clinical outcomes. Finally, the authors address the intersection of nutrition and the microbiome, exploring the use of supplemental pre-, pro-, and synbiotics to influence microbial composition and improve outcomes in critically ill and postsurgical patients.

Identifiants

pubmed: 36872003
pii: S1932-2275(22)00107-0
doi: 10.1016/j.anclin.2022.10.007
pmc: PMC10157520
mid: NIHMS1893638
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

263-281

Subventions

Organisme : NIGMS NIH HHS
ID : T32 GM075774
Pays : United States

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

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Auteurs

Mara A Serbanescu (MA)

Department of Anesthesiology, Duke University Hospital, 2301 Erwin Road, Box #3094, Durham, NC 27710, USA. Electronic address: mara.serbanescu@duke.edu.

Monica Da Silva (M)

Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, 950 Jefferson Tower, 625 19th Street South, Birmingham, AL 35249-6810, USA.

Ahmet Zaky (A)

Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, 950 Jefferson Tower, 625 19th Street South, Birmingham, AL 35249-6810, USA.

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Classifications MeSH