The immunotherapy advancement targeting malignant blastomas in early childhood.
advanced immunotherapy
childhood
chimeric-antigen based receptor cell therapy
malignant blastomas
monoclonal antibodies
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2023
2023
Historique:
received:
09
08
2022
accepted:
12
01
2023
entrez:
6
3
2023
pubmed:
7
3
2023
medline:
7
3
2023
Statut:
epublish
Résumé
Malignant blastomas develop relentlessly in all functional body organs inflicting severe health ailments in younger children. Malignant blastomas exhibit diverse clinical characteristics in compliance with their emergence in functional body organs. Surprisingly, neither of these preferred treatment types (surgery, radiotherapy, and chemotherapy) showed promise or were effective in treating malignant blastomas among child patients. N ew, innovative immunotherapeutic procedures including monoclonal antibodies and chimeric-antigen based receptor (CAR) cell therapy, coupled with the clinical study of reliable therapeutic targets and immune regulatory pathways targeting malignant blastomas, have attracted the attention of clinicians recently.
Identifiants
pubmed: 36874100
doi: 10.3389/fonc.2023.1015115
pmc: PMC9978522
doi:
Types de publication
Systematic Review
Langues
eng
Pagination
1015115Informations de copyright
Copyright © 2023 Zang, Ding, Liu, Arun Kumar, Liu, Zhou and Duan.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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