Journey to the other side of the brain: asymmetry in patients with chronic mild or moderate traumatic brain injury.
MRI
NeuroGage®
NeuroQuant®
asymmetry
traumatic brain injury (TBI)
volumetry
Journal
Concussion (London, England)
ISSN: 2056-3299
Titre abrégé: Concussion
Pays: England
ID NLM: 101672433
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
03
05
2022
accepted:
01
12
2022
entrez:
6
3
2023
pubmed:
7
3
2023
medline:
7
3
2023
Statut:
epublish
Résumé
Patients with chronic mild or moderate traumatic brain injury have some regions of brain atrophy (including cerebral white matter) but even more regions of abnormal brain enlargement (including other cerebral regions). Ipsilateral injury and atrophy cause the eventual development of contralateral compensatory hypertrophy. 50 patients with mild or moderate traumatic brain injury were compared to 80 normal controls (n = 80) with respect to MRI brain volume asymmetry. Asymmetry-based correlations were used to test the primary hypothesis. The group of patients had multiple regions of abnormal asymmetry. The correlational analyses supported the conclusion that acute injury to ipsilateral cerebral white matter regions caused atrophy, leading eventually to abnormal enlargement of contralateral regions due to compensatory hypertrophy.
Identifiants
pubmed: 36874877
doi: 10.2217/cnc-2022-0003
pmc: PMC9979152
doi:
Types de publication
Journal Article
Langues
eng
Pagination
CNC101Informations de copyright
© 2023 Virginia Institute of Neuropsychiatry.
Déclaration de conflit d'intérêts
The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed
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